Evidence map›Paper›PMID 15516917›Full record

ArticleNature medicine2004

From Pasteur to genomics: progress and challenges in infectious diseases.

Rino Rappuoli

Open access · bronzeAbstract readHistorical Article
In one paragraph

Article in Nature medicine, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 109 citations in OpenAlex.

  1. Review
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  11. Prediction of cross-species infection propensities of viruses with receptor similarity.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2019
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Vaccines, adjuvants and autoimmunity.Pharmacological research · 2015
    Review
  17. Delivering vaccines to the people who need them most.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2015
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Rino RappuoliRino Rappuoli is at Chiron Vaccines, Via Fiorentina 1, 53100 Siena, Italy. rino_rappuoli@chiron.com
Newron Pharmaceuticals (Italy) · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over the past decade, microbiology and infectious disease research have undergone the most profound revolution since the times of Pasteur. Genomic sequencing has revealed the much-awaited blueprint of most pathogens. Screening blood for the nucleic acids of infectious agents has blunted the spread of pathogens by transfusion, the field of antiviral therapeutics has exploded and technologies for the development of novel and safer vaccines have become available. The quantum jump in our ability to detect, prevent and treat infectious diseases resulting from improved technologies and genomics was moderated during this period by the greatest emergence of new infectious agents ever recorded and a worrisome increase in resistance to existing therapies. Dozens of new infectious diseases are expected to emerge in the coming decades. Controlling these diseases will require a better understanding of the worldwide threat and economic burden of infectious diseases and a global agenda.

Indexed as

GenomicsAntiviral AgentsCommunicable Disease ControlCommunicable DiseasesCommunicable Diseases, EmergingGlobal HealthHistory, 20th CenturyHistory, 21st CenturyHumansVaccinesAntiviral AgentsVaccines

Identifiers

PMID15516917
PMCPMC7096024
OpenAlexW2069010908

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.