Evidence map›Paper›PMID 15516599›Full record

ArticleJournal of bacteriology2004

Cold sensitivity of thermophilic and mesophilic RNA polymerases.

A Kulbachinskiy, I Bass, E Bogdanova, A Goldfarb, V Nikiforov

Open access · greenAbstract read
In one paragraph

Article in Journal of bacteriology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
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  10. Allosteric control of catalysis by the F loop of RNA polymerase.Proceedings of the National Academy of Sciences of the United States of America · 2009
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

A KulbachinskiyInstitute of Molecular Genetics, Moscow, Russia. akulb@img.ras.ru
I Bass
E Bogdanova
A Goldfarb
V Nikiforov
Institute of Molecular Genetics · RUInternational Center for Public Health · US

Funding

Structure and Function of RNA Polymerases in E ColiR01GM030717 · NIGMS · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI MUSTAEV, ARKADY · 1985 to 2011
$4.8M
NIGMS NIH HHS GM30717NIGMS NIH HHS R01 GM030717
6 · The paper itself

Abstract

RNA polymerase from mesophilic Deinococcus radiodurans displays the same cold sensitivity of promoter opening as RNA polymerase from the closely related thermophilic Thermus aquaticus. This suggests that, contrary to the accepted view, cold sensitivity of promoter opening by thermophilic RNA polymerases may not be a consequence of their thermostability.

Indexed as

Cold TemperatureDeinococcusDNA-Directed RNA PolymerasesEnzyme StabilityHot TemperaturePromoter Regions, GeneticRNA, BacterialThermusTranscription, GeneticDNA-Directed RNA PolymerasesRNA, Bacterial

Identifiers

PMID15516599
PMCPMC524896
OpenAlexW2103220427

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.