ArticlePlant physiology2004
Molecular physiological analysis of the two plastidic ATP/ADP transporters from Arabidopsis.
Article in Plant physiology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.
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52 citing papers in PubMed, 134 citations in OpenAlex.
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- Five unaddressed questions about cytokinin biosynthesis.Journal of experimental botany · 2025Review
- Symplasmic phloem loading and subcellular transport in storage roots are key factors for carbon allocation in cassava.Plant physiology · 2024Article
- Development of a CRISPR/Cas9-mediated gene-editing method to isolate a mutant of the unicellular green alga Parachlorella kessleri strain NIES-2152 with improved lipid productivity.Biotechnology for biofuels and bioproducts · 2024Article
- Bioenergetics of pollen tube growth in Arabidopsis thaliana revealed by ratiometric genetically encoded biosensors.Nature communications · 2022Article
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- Loss of a pyridoxal-phosphate phosphatase rescues Arabidopsis lacking an endoplasmic reticulum ATP carrier.Plant physiology · 2022Article
- Arabidopsis guard cell chloroplasts import cytosolic ATP for starch turnover and stomatal opening.Nature communications · 2022Article
- Integrated physiological and weighted gene co-expression network analysis reveals the hub genes engaged in nitrate-regulated alleviation of ammonium toxicity at the seedling stage in wheat (Frontiers in plant science · 2022Article
- Identification of Chloroplast Envelope Proteins with Critical Importance for Cold Acclimation.Plant physiology · 2020Article
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- ATP translocation and chloroplast biology.National science review · 2019Article
- Malate valves: old shuttles with new perspectives.Plant biology (Stuttgart, Germany) · 2019Review
- Comprehensive evaluation of fuel properties and complex regulation of intracellular transporters for high oil production in developing seeds ofBiotechnology for biofuels · 2019Article
- ATP compartmentation in plastids and cytosol ofProceedings of the National Academy of Sciences of the United States of America · 2018Article
- Article
- Ion and metabolite transport in the chloroplast of algae: lessons from land plants.Cellular and molecular life sciences : CMLS · 2018Review
- ATP sensing in living plant cells reveals tissue gradients and stress dynamics of energy physiology.eLife · 2017Article
- Integrated analysis of 454 and Illumina transcriptomic sequencing characterizes carbon flux and energy source for fatty acid synthesis in developingBiotechnology for biofuels · 2017Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Arabidopsis (Arabidopsis thaliana) possesses two isoforms of plastidic ATP/ADP transporters (AtNTT1 and AtNTT2) exhibiting similar biochemical properties. To analyze the function of both isoforms on the molecular level, we examined the expression pattern of both genes by northern-blot analysis and promoter-beta-glucuronidase fusions. AtNTT1 represents a sugar-induced gene mainly expressed in stem and roots, whereas AtNTT2 is expressed in several Arabidopsis tissues with highest accumulation in developing roots and young cotyledons. Developing lipid-storing seeds hardly contained AtNTT1 or -2 transcripts. The absence of a functional AtNTT1 gene affected plant development only slightly, whereas AtNTT2T-DNA, AtNTT1-2T-DNA, and RNA interference (RNAi) plants showed retarded plant development, mainly characterized by a reduced ability to generate primary roots and a delayed chlorophyll accumulation in seedlings. Electron microscopic examination of chloroplast substructure also revealed an impaired formation of thylakoids in RNAi seedlings. Moreover, RNAi- and AtNTT1-2T-DNA plants showed reduced accumulation of the nuclear-encoded protein CP24 during deetiolation. Under short-day conditions reduced plastidic ATP import capacity correlates with a substantially reduced plant growth rate. This effect is absent under long-day conditions, strikingly indicating that nocturnal ATP import into chloroplasts is important. Plastidic ATP/ADP transport activity exerts significant control on lipid synthesis in developing Arabidopsis seeds. In total we made the surprising observation that plastidic ATP/ADP transport activity is not required to pass through the complete plant life cycle. However, plastidic ATP/ADP-transporter activity is required for both an undisturbed development of young tissues and a controlled cellular metabolism in mature leaves.
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