ArticleThorax2004
When can personal best peak flow be determined for asthma action plans?
Article in Thorax, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06116292 (Impact of the Implementation of a Telemedicine Program on Patients Diagnosed with Asthma), which is not on this map. Cited by 8 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Impact of the Implementation of a Telemedicine Program on Patients Diagnosed with Asthma
Who cites it
8 citing papers in PubMed.
- Impact of the implementation of a telemedicine program on patients diagnosed with asthma.BMC pulmonary medicine · 2024Trial
- Continuous positive airway pressure acutely increases exercise duration in children with severe therapy-resistant asthma: a randomized crossover trial.World journal of pediatrics : WJP · 2021Trial
- Efficacy and safety of AZD7594, an inhaled non-steroidal selective glucocorticoid receptor modulator, in patients with asthma: a phase 2a randomized, double blind, placebo-controlled crossover trial.Respiratory research · 2019Trial
- Domiciliary monitoring of exhaled nitric oxide in the management of asthma: a pilot study.BMC pulmonary medicine · 2024Article
- Utility of biomarkers in the diagnosis and monitoring of asthmatic children.The World Allergy Organization journal · 2023Review
- Tools in Asthma Evaluation and Management: When and How to Use Them?Indian journal of pediatrics · 2018Review
- Asthma Control Assessment in Children: Correlation between Asthma Control Test and Peak Expiratory Flow.Maedica · 2014Article
- GEMA 5.3. Spanish Guideline on the Management of Asthma.Open respiratory archivesArticle
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3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWritten asthma action plans based on personal best peak expiratory flow (PEF) consistently improve health outcomes, whereas those based on predicted PEF do not. Guidelines state that personal best PEF should be assessed over 2-3 weeks during good asthma control, but it is unclear how long to wait after commencing or changing treatment.
methodsElectronically recorded spirometric data from 61 subjects with initially poorly controlled asthma from a 72 week budesonide study were analysed. For each week, average morning pre-bronchodilator PEF was calculated and personal best PEF was determined as the highest PEF in the previous 2 weeks. The time to plateau was defined as the week beyond which no further improvement occurred.
resultsAt baseline, average morning PEF was 61% predicted and personal best PEF was 87% predicted. Personal best PEF from twice daily monitoring increased to a plateau of 95% predicted (p<0.0001) after only 3 weeks of budesonide treatment. However, average morning PEF continued to improve for 3 months and "as needed" reliever use for 7 months.
conclusionsPersonal best PEF is a useful concept for asthma self-management plans when determined as the highest PEF over the previous 2 weeks. With twice daily monitoring, personal best PEF reaches plateau levels after only a few weeks of corticosteroid treatment.
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