ArticleThe Canadian veterinary journal = La revue veterinaire canadienne2004
The variability of serological and molecular diagnosis of feline immunodeficiency virus infection.
Article in The Canadian veterinary journal = La revue veterinaire canadienne, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- Comparative evaluation of nine lateral flow assays for FIV antibody detection using an in-house ELISA as a reference method.BMC veterinary research · 2026Article
- A New Rapid Indirect ELISA Test for Serological Diagnosis of Feline Immunodeficiency.Veterinary sciences · 2025Article
- Article
- Commercially Available Enzyme-Linked Immunosorbent Assay and Polymerase Chain Reaction Tests for Detection of Feline Immunodeficiency Virus Infection.Journal of veterinary internal medicine · 2017Article
- Feline immunodeficiency virus (FIV) env recombinants are common in natural infections.Retrovirology · 2014Article
- Preliminary evaluation of a quantitative polymerase chain reaction assay for diagnosis of feline immunodeficiency virus infection.Journal of feline medicine and surgery · 2013Article
- Feline leukemia virus and feline immunodeficiency virus in Canada: recommendations for testing and management.The Canadian veterinary journal = La revue veterinaire canadienne · 2011Review
- Feline immunodeficiency. ABCD guidelines on prevention and management.Journal of feline medicine and surgery · 2009Review
- Seroprevalence of feline leukemia virus and feline immunodeficiency virus infection among cats in Canada.The Canadian veterinary journal = La revue veterinaire canadienne · 2009Article
- Ring tests to evaluate the performance of Porcine circovirus-2 (PCV-2) polymerase chain reaction (PCR) assays used in North American diagnostic laboratories.Canadian journal of veterinary research = Revue canadienne de recherche veterinaire · 2009Article
- 2008 American Association of Feline Practitioners' feline retrovirus management guidelines.Journal of feline medicine and surgery · 2008Article
- Evaluation of a novel nested PCR for the routine diagnosis of feline leukemia virus (FeLV) and feline immunodeficiency virus (FIV).Journal of feline medicine and surgery · 2007Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diagnosis of feline immunodeficiency virus (FIV) infection by polymerase chain reaction (PCR) has recently become available, but little is known about the performance of this assay. The purpose of this study was to determine the sensitivity and specificity of PCR diagnosis of FIV infection. Replicate aliquots of blood samples from cats identified as FIV positive or negative by 2 previous enzyme-linked immunosorbent assay (ELISA) results, and from clinically healthy dogs, were submitted to different laboratories for FIV serologic diagnosis and PCR. The PCR products obtained in 1 laboratory were sequenced to determine the FIV subtype. The PCR assays correctly identified 100%, 80%, and 50% of the FIV-positive samples, and 100%, 90%, and 70% of FIV-negative samples. Each dog sample was reported as FIV PCR positive at least once, and FIV subtypes A, B, and C were identified. It was concluded that PCR tests currently available for FIV infection are unreliable, with highly variable sensitivity and specificity.
Indexed as
Identifiers
15510684PMC545975What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.