ArticleJournal of clinical pathology2004
Serrated adenoma of the duodenum.
Article in Journal of clinical pathology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 34 citations in OpenAlex.
- Article
- Two duodenal sessile serrated lesions in a patient with serrated polyposis syndrome: case report and review of the literature.Clinical journal of gastroenterology · 2025Review
- Article
- Histopathological Complexities and Diagnostic Challenges in Familial Adenomatous Polyposis: A Case Report.Cureus · 2024Article
- Article
- Article
- Traditional Serrated Adenoma of the Gallbladder, a Case Report.Pathology oncology research : POR · 2022Article
- Small Bowel Epithelial Precursor Lesions: A Focus on Molecular Alterations.International journal of molecular sciences · 2021Review
- Gastric and small intestinal traditional serrated adenomas: a detailed morphologic and immunohistochemical analysis.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2020Article
- Clinical features of upper gastrointestinal serrated lesions: An endoscopy database analysis of 98746 patients.World journal of gastroenterology · 2016Article
- Traditional serrated adenomas of the upper digestive tract.Journal of clinical pathology · 2016Review
- [Serrated polyps of the duodenum. Three cases with immunohistological and molecular pathological findings].Der Pathologe · 2013Article
- Serrated adenoma of the stomach: Case report and literature review.World journal of gastrointestinal endoscopy · 2013Article
- Evaluation of non-ampullary duodenal polyps: comparison of non-neoplastic and neoplastic lesions.World journal of gastroenterology · 2010Article
- Stem cells might participate in the cell turnover of duodenal adenomas.International journal of clinical and experimental pathology · 2009Article
- Gastric duodenal metaplasia in duodenal adenomas.Journal of clinical pathology · 2007Article
- Hyperplastic polyps of the duodenum: an unusual histological finding.Journal of clinical pathology · 2006Article
- Jejunal Serrated Adenoma Diagnosed and Treated by Double-Balloon Enteroscopy.Case reports in gastroenterologyArticle
- Slow-Growing Early Adenocarcinoma Arising from Traditional Serrated Adenoma in the Duodenum.Case reports in gastroenterologyArticle
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The duodenum is the most common site for extracolonic adenomas in patients with familial adenomatous polyposis (FAP). These adenomas are usually tubular, villous, or tubulovillous. This report describes a patient with FAP who had a duodenal adenoma with a different histology--it had the microscopic attributes of a serrated adenoma--tumours that are relatively common in the colorectal mucosa and are occasionally found in the stomach. A 78 year old man with FAP and multiple adenomas was colectomised and the rectum amputated. Several years later he developed silent jaundice. The surgical specimen showed an adenomatous growth juxtaposing the papilla of Vater. The adenoma had epithelial fronds with crenated, sawtooth-like configurations caused by scalloped epithelial infolding. The nuclei covering the notched fronds were pleomorphic, stratified, either cigar shaped with irregular chromatin deposits or vesicular shaped with a large nucleolus. One area showed involvement of a duct by neoplastic epithelium with extension into periluminal glands. No invasive carcinoma was present. Serrated adenomas differ from tubular and villous adenomas in their histological organisation and their initial pattern of cell proliferation and genotypic aberration. Increased awareness of the existence of serrated neoplasms in the duodenum may result in similar cases being reported in the future.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.