Evidence map›Paper›PMID 15509461›Full record

ReviewCurrent pain and headache reports2004

An expansion of Simons' integrated hypothesis of trigger point formation.

Robert D Gerwin, Jan Dommerholt, Jay P Shah

4 registry-linked trialsAbstract readReview
PubMed Publisher
In one paragraph

Review in Current pain and headache reports, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 120 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
120citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02889991 nacompletednot on this mapstarted 2016, after this paper: background citation

Comparative Study, Between Dry Needling Techniques, in the Evolution of Myofascial Pain Shoulder in Athletes. Elastography as Indicator in the Repair of Myofascial Tissue, Post-dry Needling.

TypeinterventionalSponsorUniversity of the Basque Country (UPV/EHU)Ran2016 to 2017Enrolled77ConditionsMyofascial Pain Syndromes, Dry Needling, Technique for the Treatment of the Myofascial Trigger Points, ElastographyArmsHigh Intensity Dry Needling, Low intensity Dry Needling, Fascial Mechanotransduction Dry Needling, Technique Placebo of Dry Needling
NCT03944889 early_phase1completednot on this mapstarted 2019, after this paper: background citation

Quantitative Response of Healthy Muscle Following the Induction of Capsaicin

TypeinterventionalSponsorToronto Rehabilitation InstituteRan2019 to 2020Enrolled20ConditionsCentral SensitisationArmsCapsaicin, Delsys Trigno Galileo System, Cadwell Sierra Wave, Sonosite Ultrasound Machine, Goniometer
NCT05646160 naunknown statusnot on this mapstarted 2018, after this paper: background citation

Effects of Myofascial Trigger Points Therapy in Migraine.

TypeinterventionalSponsorJózef Piłsudski University of Physical EducationRan2018 to 2023Enrolled100ConditionsMigraine, Pain, Shoulder, Trapezius Muscle Strain Left, Trapezius Muscle Strain RightArmsIschemic Compression of Myofascial Trigger Points (IC-MTRPs)
NCT06060925 completednot on this mapstarted 2023, after this paper: background citation

Multimodal Imaging Biomarkers for Investigating Fascia, Muscle and Vasculature in Myofascial Pain

TypeobservationalSponsorGeorge Mason UniversityRan2023 to 2025Enrolled96ConditionsMyofascial Pain Syndrome, HealthyArmsUltrasound imaging, Bioimpedance spectroscopy, Electromyography, Physical examination
3 · Its place in the literature

Who cites it

120 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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  3. Assessment of Myofascial Trigger Points via Imaging: A Systematic Review.American journal of physical medicine & rehabilitation · 2021
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60 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Robert D GerwinJohns Hopkins University Pain and Rehabilitation Medicine, Bethesda, MD 20814-2432, USA. gerwin@painpoints.com
Jan Dommerholt
Jay P Shah

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Simons' integrated hypothesis proposed a model of trigger point (TrP) activation to explain known TrP phenomena, particularly endplate noise. We propose an expansion of this hypothesis to account for new experimental data and established muscle pathophysiology.

Indexed as

AcetylcholineAcetylcholinesteraseAnimalsCalcitonin Gene-Related PeptideHumansHydrogen-Ion ConcentrationMotor EndplateMuscle ContractionMuscle, SkeletalMyofascial Pain SyndromesNociceptorsReceptors, CholinergicAcetylcholineAcetylcholinesteraseCalcitonin Gene-Related PeptideReceptors, Cholinergic

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.