The echinocandin "target" identified by cross-linking is a homolog of Pil1 and Lsp1, sphingolipid-dependent regulators of cell wall integrity signaling.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

11 citing papers in PubMed.

1. Specific substitutions in the echinocandin target Fks1p account for reduced susceptibility of rare laboratory and clinical Candida sp. isolates.Antimicrobial agents and chemotherapy · 2005
   Trial
2. Proteomic Analysis of Caspofungin-Induced Responses in Planktonic Cells and Biofilms ofFrontiers in microbiology · 2021
   Article
3. Characterization of AnNce102 and its role in eisosome stability and sphingolipid biosynthesis.Scientific reports · 2015
   Article
4. CRS-MIS in Candida glabrata: sphingolipids modulate echinocandin-Fks interaction.Molecular microbiology · 2012
   Article
5. Topological and mutational analysis of Saccharomyces cerevisiae Fks1.Eukaryotic cell · 2012
   Article
6. Sur7 promotes plasma membrane organization and is needed for resistance to stressful conditions and to the invasive growth and virulence of Candida albicans.mBio · 2012
   Article
7. Current perspectives on echinocandin class drugs.Future microbiology · 2011
   Review
8. The Candida albicans Sur7 protein is needed for proper synthesis of the fibrillar component of the cell wall that confers strength.Eukaryotic cell · 2011
   Article
9. The Sur7 protein regulates plasma membrane organization and prevents intracellular cell wall growth in Candida albicans.Molecular biology of the cell · 2008
   Article
10. Modes of action of the new arylguanidine abafungin beyond interference with ergosterol biosynthesis and in vitro activity against medically important fungi.Chemotherapy · 2008
    Article
11. Resistance to echinocandin-class antifungal drugs.Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy · 2007
    Review

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

2 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as