Evidence map›Paper›PMID 15504880›Full record

ArticleAntimicrobial agents and chemotherapy2004

Antimicrobial and antileishmanial activities of hypocrellins A and B.

Guoyi Ma, Shabana I Khan, Melissa R Jacob, Babu L Tekwani, Zuqiang Li, David S Pasco, Larry A Walker, Ikhlas A Khan

Abstract readComparative Study
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Fungal perylenequinones.Mycological progress · 2022
    Review
  11. Review
  12. Review
  13. Phylogenetic Position ofJournal of fungi (Basel, Switzerland) · 2021
    Article
  14. Article
  15. FeInternational journal of molecular sciences · 2021
    Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Guoyi MaThe National Center for Natural Products Research, School of Pharmacy, The University of Mississippi, University, MS 38677, USA.
Shabana I Khan
Melissa R Jacob
Babu L Tekwani
Zuqiang Li
David S Pasco
Larry A Walker
Ikhlas A Khan

Funding

ODCDC CDC HHS UR3/CCU 418652ODCDC CDC HHS USO/CCV 418839
6 · The paper itself

Abstract

Hypocrellins A and B were evaluated for in vitro antimicrobial and antileishmanial activities. Hypocrellin A exhibited promising activity against Candida albicans and moderate activity against Staphylococcus aureus, methicillin-resistant S. aureus, Pseudomonas aeruginosa, and Mycobacterium intracellulare. Hypocrellin B showed weak antimicrobial activities. Hypocrellin A exhibited potent antileishmanial activity, while hypocrellin B was only moderately active. These results of promising antifungal and antileishmanial activity of hypocrellin A may be useful for further structure-activity relationship and in vivo studies.

Indexed as

AnimalsAnti-Infective AgentsAntiprotozoal AgentsBacteriaFungiLeishmania donovaniMicrobial Sensitivity TestsOpportunistic InfectionsPerylenePhenolQuinonesAnti-Infective AgentsAntiprotozoal Agentshypocrellin Ahypocrellin BPerylenePhenolQuinones

Identifiers

PMID15504880
PMCPMC525422

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.