ArticleAntimicrobial agents and chemotherapy2004
Novel mutations within the embB gene in ethambutol-susceptible clinical isolates of Mycobacterium tuberculosis.
Article in Antimicrobial agents and chemotherapy, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Diagnostic accuracy of a molecular drug susceptibility testing method for the antituberculosis drug ethambutol: a systematic review and meta-analysis.Journal of clinical microbiology · 2014Pooled it
- Advancing against drug-resistant tuberculosis: an extensive review, novel strategies and patent landscape.Naunyn-Schmiedeberg's archives of pharmacology · 2025Review
- Drug selection based on pan-genomics genetic features ofFrontiers in microbiology · 2025Article
- Structural dynamics insights into the M306L, M306V, and D1024N mutations in Mycobacterium tuberculosis inducing resistance to ethambutol.Genomics & informatics · 2023Article
- Frequency of Codon 306 Mutations inInternational journal of preventive medicine · 2020Review
- Evaluation of Whole-Genome Sequence Method to Diagnose Resistance of 13 Anti-tuberculosis Drugs and Characterize Resistance Genes in Clinical Multi-Drug ResistanceFrontiers in microbiology · 2019Article
- A Chip for Detecting Tuberculosis Drug Resistance Based on Polymerase Chain Reaction (PCR)-Magnetic Bead Molecule Platform.Frontiers in microbiology · 2018Article
- Mutations withinAntimicrobial agents and chemotherapy · 2018Article
- Association between embB Codon 306 Mutations, Phenotypic Resistance Profiles, and Genotypic Characterization in Clinical Mycobacterium tuberculosis Isolates from Hebei, China.Antimicrobial agents and chemotherapy · 2016Article
- Prevalence and molecular characteristics of drug-resistant Mycobacterium tuberculosis in Beijing, China: 2006 versus 2012.BMC microbiology · 2016Article
- Whole genome sequence analysis of multidrug-resistant Mycobacterium tuberculosis Beijing isolates from an outbreak in Thailand.Molecular genetics and genomics : MGG · 2015Article
- Mutation at embB codon 306, a potential marker for the identification of multidrug resistance associated with ethambutol in Mycobacterium tuberculosis.Antimicrobial agents and chemotherapy · 2015Article
- Molecular Analysis of the embCAB Locus and embR Gene Involved in Ethambutol Resistance in Clinical Isolates of Mycobacterium tuberculosis in France.Antimicrobial agents and chemotherapy · 2015Article
- Analysis of embCAB mutations associated with ethambutol resistance in multidrug-resistant mycobacterium tuberculosis isolates from China.Antimicrobial agents and chemotherapy · 2015Article
- Mutations in the embB gene and their association with ethambutol resistance in multidrug-resistant Mycobacterium tuberculosis clinical isolates from Poland.BioMed research international · 2013Article
- High-resolution melting analysis for the rapid detection of fluoroquinolone and streptomycin resistance in Mycobacterium tuberculosis.PloS one · 2012Article
- Characteristics of embB mutations in multidrug-resistant Mycobacterium tuberculosis isolates in Henan, China.The Journal of antimicrobial chemotherapy · 2011Article
- Allelic exchange and mutant selection demonstrate that common clinical embCAB gene mutations only modestly increase resistance to ethambutol in Mycobacterium tuberculosis.Antimicrobial agents and chemotherapy · 2010Article
- The arabinosyltransferase EmbC is inhibited by ethambutol in Mycobacterium tuberculosis.Antimicrobial agents and chemotherapy · 2009Article
- Mutations at embB codon 306 are an important molecular indicator of ethambutol resistance in Mycobacterium tuberculosis.Antimicrobial agents and chemotherapy · 2009Article
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4 authors.
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Abstract
Genetic analysis of the embB gene revealed mutations in 17 (68%) of 25 ethambutol (EMB) resistant isolates (M306I, M306V, M306L, Q497R) but also in 4 (20%) of 20 EMB-susceptible isolates of Mycobacterium tuberculosis, namely, an ATG-->ATM substitution resulting in M306I, G406N, and the novel alterations M423I and A659T.
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