ArticleJournal of comparative physiology. B, Biochemical, systemic, and environmental physiology2004
Short-term fasting induces intra-hepatic lipid accumulation and decreases intestinal mass without reduced brush-border enzyme activity in mink (Mustela vison) small intestine.
Article in Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 39 citations in OpenAlex.
- Starvation-resistant cavefish reveal conserved mechanisms of starvation-induced hepatic lipotoxicity.Life science alliance · 2024Article
- Starvation resistant cavefish reveal conserved mechanisms of starvation-induced hepatic lipotoxicity.bioRxiv : the preprint server for biology · 2024Article
- A Model Construction of Starvation Induces Hepatic Steatosis and Transcriptome Analysis in Zebrafish Larvae.Biology · 2021Article
- The gastrointestinal tract of farmed mink (Neovison vison) maintains a diverse mucosa-associated microbiota following a 3-day fasting period.MicrobiologyOpen · 2017Article
- Evidence of endoplasmic reticulum stress and liver inflammation in the American mink Neovison vison with benign hepatic steatosis.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2014Article
- Ribosomal protein-Mdm2-p53 pathway coordinates nutrient stress with lipid metabolism by regulating MCD and promoting fatty acid oxidation.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- Article
- Fasting in the American marten (Martes americana): a physiological model of the adaptations of a lean-bodied animal.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2007Article
- Modulations in the intestinal disaccharide hydrolases and membrane dynamics: effect of non-steroidal anti-inflammatory drugs aspirin and nimesulide.Molecular and cellular biochemistry · 2007Article
- Adaptations to fasting in the American mink (Mustela vison): nitrogen metabolism.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2005Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
For many mammalian species short-term fasting is associated with intestinal atrophy and decreased digestive capacity. Under natural conditions, strictly carnivorous animals often experience prey scarcity during winter, and they may therefore be particularly well adapted to short-term food deprivation. To examine how the carnivorous gastrointestinal tract is affected by fasting, small-intestinal structure, brush-border enzyme activities and hepatic structure and function were examined in fed mink (controls) and mink that had been fasted for 1-10 days. During the first 1-2 days of fasting, intestinal mass decreased more rapidly than total body mass and villus heights were reduced 25-40%. In contrast, tissue-specific activity of the brush-border enzymes sucrase, maltase, lactase, aminopeptidase A and dipeptidylpeptidase IV increased 0.5- to 1.5-fold at this time, but returned to prefasting levels after 6 days of fasting. After 6-10 days of fasting there was a marked increase in the activity of hepatic enzymes and accumulation of intra-hepatic lipid vacuoles. Thus, mink may be a useful model for studying fasting-induced intestinal atrophy and adaptation as well as mechanisms involved in accumulation of intra-hepatic lipids following food deprivation in strictly carnivorous domestic mammals, such as cats and ferrets.
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