Animal models have little to teach us about type 1 diabetes: 2. In opposition to this proposal.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

1. Diabetes mellitus, hearing loss, and therapeutic interventions: A systematic review of insights from preclinical animal models.PloS one · 2024
   Pooled it
2. Revisiting type 1 diabetes progression in the non-obese diabetic mouse.Scientific reports · 2026
   Article
3. Bridging the Gap: Pancreas Tissue Slices From Organ and Tissue Donors for the Study of Diabetes Pathogenesis.Diabetes · 2024
   Review
4. NOD mice have distinct metabolic and immunologic profiles when compared with genetically similar MHC-matched ICR mice.American journal of physiology. Endocrinology and metabolism · 2023
   Article
5. Modelling the endocrine pancreas in health and disease.Nature reviews. Endocrinology · 2019
   Review
6. Genome annotation for clinical genomic diagnostics: strengths and weaknesses.Genome medicine · 2017
   Review
7. Insulitis in human type 1 diabetes: a comparison between patients and animal models.Seminars in immunopathology · 2014
   Review
8. Impact of dietary gluten on regulatory T cells and Th17 cells in BALB/c mice.PloS one · 2012
   Article
9. Immunotherapy for the prevention and treatment of type 1 diabetes: optimizing the path from bench to bedside.Diabetes care · 2009
   Article
10. From beast to bedside: a commentary.Diabetologia · 2004
    Review
11. Pathogenesis of Type 1 Diabetes Mellitus and Rodent Experimental Models.Acta naturae
    Article

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

2 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as