ArticleBiophysical journal2005
Diffusion in two-component lipid membranes--a fluorescence correlation spectroscopy and monte carlo simulation study.
Article in Biophysical journal, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 106 citations in OpenAlex.
- Influence of Lipomannan and Lipoarabinomannan Concentration on Mycobacterial Inner Membranes Characterized by All-atom Simulations.bioRxiv : the preprint server for biology · 2026Article
- Cholesterol tunes lipid bilayer interactions.RSC advances · 2026Article
- Numerical Simulation and FRAP Experiments Show That the Plasma Membrane Binding Protein PH-EFA6 Does Not Exhibit Anomalous Subdiffusion in Cells.Biomolecules · 2018Article
- Phase-Separated Liposomes Enhance the Efficiency of Macromolecular Delivery to the Cellular Cytoplasm.Cellular and molecular bioengineering · 2017Article
- Crowding-Induced Mixing Behavior of Lipid Bilayers: Examination of Mixing Energy, Phase, Packing Geometry, and Reversibility.Langmuir : the ACS journal of surfaces and colloids · 2016Article
- Single Molecule 3D Orientation in Time and Space: A 6D Dynamic Study on Fluorescently Labeled Lipid Membranes.Journal of fluorescence · 2016Article
- Steric Pressure among Membrane-Bound Polymers Opposes Lipid Phase Separation.Langmuir : the ACS journal of surfaces and colloids · 2016Article
- Bayesian model selection applied to the analysis of fluorescence correlation spectroscopy data of fluorescent proteins in vitro and in vivo.Analytical chemistry · 2015Article
- Computer simulations suggest a key role of membranous nanodomains in biliary lipid secretion.PLoS computational biology · 2015Article
- Chromatin insulator factors involved in long-range DNA interactions and their role in the folding of the Drosophila genome.PLoS genetics · 2014Article
- Article
- Sorting of lipidated peptides in fluid bilayers: a molecular-level investigation.Journal of the American Chemical Society · 2012Article
- Regulation from within: the cytoskeleton in transmembrane signaling.Trends in cell biology · 2012Review
- Phase separation and fluctuations in mixtures of a saturated and an unsaturated phospholipid.Biophysical journal · 2012Article
- Fluorescence correlation spectroscopy: a review of biochemical and microfluidic applications.Applied spectroscopy · 2011Review
- FCS diffusion laws in two-phase lipid membranes: determination of domain mean size by experiments and Monte Carlo simulations.Biophysical journal · 2011Article
- Near-critical fluctuations and cytoskeleton-assisted phase separation lead to subdiffusion in cell membranes.Biophysical journal · 2011Article
- Steric confinement of proteins on lipid membranes can drive curvature and tubulation.Proceedings of the National Academy of Sciences of the United States of America · 2010Article
- Peripheral protein organization and its influence on lipid diffusion in biomimetic membranes.ACS chemical biology · 2010Article
- Lipid bilayer membrane-triggered presynaptic vesicle assembly.ACS chemical neuroscience · 2010Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Using fluorescence correlation spectroscopy, calorimetry, and Monte Carlo simulations, we studied diffusion processes in two-component membranes close to the chain melting transition. The aim is to describe complex diffusion behavior in lipid systems in which gel and fluid domains coexist. Diffusion processes in gel membranes are significantly slower than in fluid membranes. Diffusion processes in mixed phase regions are therefore expected to be complex. Due to statistical fluctuations the gel-fluid domain patterns are not uniform in space and time. No models for such diffusion processes are available. In this article, which is both experimental and theoretical, we investigated the diffusion in DMPC-DSPC lipid mixtures as a function of temperature and composition. We then modeled the fluorescence correlation spectroscopy experiment using Monte Carlo simulations to analyze the diffusion process. It is shown that the simulations yield a very good description of the experimental diffusion processes, and that predicted autocorrelation profiles are superimposable with the experimental curves. We believe that this study adds to the discussion on the physical nature of rafts found in biomembranes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.