Evidence map›Paper›PMID 15501802›Full record

ArticleInfection and immunity2004

Shiga toxin binding to isolated porcine tissues and peripheral blood leukocytes.

Kellie R K Winter, William C Stoffregen, Evelyn A Dean-Nystrom

Open access · greenAbstract read
In one paragraph

Article in Infection and immunity, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Shiga Toxin, Stx2e, Influences the Activity of Porcine Lymphocytes In Vitro.International journal of molecular sciences · 2023
    Article
  3. The Role ofToxins · 2020
    Review
  4. Molecular Biology ofToxins · 2020
    Review
  5. Structural Insights intoMicroorganisms · 2019
    Article
  6. LPS-primed CD11bScientific reports · 2018
    Article
  7. Article
  8. Article
  9. Review
  10. Role of Shiga/Vero toxins in pathogenesis.Microbiology spectrum · 2014
    Review
  11. Article
  12. Review
  13. Shiga toxin pathogenesis: kidney complications and renal failure.Current topics in microbiology and immunology · 2012
    Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Kellie R K WinterDepartment of Veterinary Microbiology and Preventive Medicine, Iowa State University, USDA Agricultural Research Service, National Animal Disease Center, Ames 50010-0070, USA.
William C Stoffregen
Evelyn A Dean-Nystrom
Agricultural Research Service · USIowa State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Shiga toxin (Stx) binding sites in porcine tissues and leukocytes were identified by the use of Stx overlay and anti-CD77/Gb3 immunoassays. Stx1 and Stx2 bound to similar tissue locations and leukocytes, although some differences were noted. Previously unreported Stx binding sites were identified in kidney tubules, intestinal lymphoid aggregates, sinusoidal liver cells, alveolar macrophages, and peripheral blood leukocytes.

Indexed as

AnimalsBinding SitesHepatocytesImmunoassayKidney TubulesLeukocytes, MononuclearMacrophages, AlveolarOrgan SpecificityShiga Toxin 1Shiga Toxin 2SwineTrihexosylceramidesglobotriaosylceramideShiga Toxin 1Shiga Toxin 2Trihexosylceramides

Identifiers

PMID15501802
PMCPMC523021
OpenAlexW2146647105

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.