Evidence map›Paper›PMID 15499066›Full record

ArticleArchives of disease in childhood2004

The incidence and mortality for meningococcal disease associated with area deprivation: an ecological study of hospital episode statistics.

R S Heyderman, Y Ben-Shlomo, C A Brennan, M Somerset

Abstract read
In one paragraph

Article in Archives of disease in childhood, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Factors associated with potentially missed acute deterioration in primary care: cohort study of UK general practices.The British journal of general practice : the journal of the Royal College of General Practitioners · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

R S HeydermanDepartment of Pathology & Microbiology, School of Medical Sciences, University of Bristol, University Walk, UK. r.heyderman@bristol.ac.uk
Y Ben-Shlomo
C A Brennan
M Somerset

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo determine whether incidence, mortality, and case fatality for meningococcal disease (MD) differs by area deprivation, and if this has changed over time.

methodsThe population of children aged less than 5 years with MD was analysed as quintiles of area deprivation scores over two time periods, 1995-99 and 1991-94. Annual age standardised rates were calculated and the association between incidence, mortality, and area deprivation quintiles assessed using Poisson regression and the risk ratios determined. Case fatality was calculated from the odds ratio of mortality by area deprivation score for the two time periods.

resultsThere were 10,524 cases of MD and 441 deaths (4.2%). Incidence rates were higher for 1995-99 (45.4 per 100,000) compared to 1991-94 (27.4 per 100,000). Mortality rates remained stable over time, indicating a decline in risk of death of around 40%. The incidence rates for the most deprived quintile were around twice those for the most affluent quintile, but this gradient declined over time. A threefold gradient was seen for mortality rates across the top and bottom quintiles, which was constant over time. The odds of mortality did not show a linear pattern, with mortality being lowest in the first and highest in the second and fifth area deprivation quintiles.

conclusionsThese data show that MD incidence and mortality are socially patterned. The determinants of case fatality are more complex and require further investigation.

Indexed as

Poverty AreasChild, PreschoolEnglandFemaleHospitalizationHumansIncidenceInfantInfant, NewbornMaleMeningococcal InfectionsMortalityOdds RatioRisk FactorsSocioeconomic Factors

Identifiers

PMID15499066
PMCPMC1719724

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.