ReviewThe Journal of physiology2005
Background synaptic activity in rat entorhinal cortical neurones: differential control of transmitter release by presynaptic receptors.
Review in The Journal of physiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 30 citations in OpenAlex.
- Multicoding in neural information transfer suggested by mathematical analysis of the frequency-dependent synaptic plasticity in vivo.Scientific reports · 2020Article
- Effects of site-specific infusions of methionine sulfoximine on the temporal progression of seizures in a rat model of mesial temporal lobe epilepsy.Epilepsy research · 2015Article
- Activity-dependent changes in excitability of perirhinal cortex networks in vitro.Pflugers Archiv : European journal of physiology · 2015Article
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- In silico pharmacology: drug design and discovery's gate to the future.In silico pharmacology · 2013Article
- All layers of medial entorhinal cortex receive presubicular and parasubicular inputs.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012Article
- Depolarising and hyperpolarising actions of GABA(A) receptor activation on gonadotrophin-releasing hormone neurones: towards an emerging consensus.Journal of neuroendocrinology · 2011Review
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- Artificial synaptic conductances reduce subthreshold oscillations and periodic firing in stellate cells of the entorhinal cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2008Article
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- Theta phase coding in a network model of the entorhinal cortex layer II with entorhinal-hippocampal loop connections.Cognitive neurodynamics · 2007Article
- Structure/function correlates of neuronal and network activity--an overview.The Journal of physiology · 2005Article
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
The entorhinal cortex (EC) is a key brain area controlling both hippocampal input and output via neurones in layer II and layer V, respectively. It is also a pivotal area in the generation and propagation of epilepsies involving the temporal lobe. We have previously shown that within the network of the EC, neurones in layer V are subject to powerful synaptic excitation but weak inhibition, whereas the reverse is true in layer II. The deep layers are also highly susceptible to acutely provoked epileptogenesis. Considerable evidence now points to a role of spontaneous background synaptic activity in control of neuronal, and hence network, excitability. In the present article we describe results of studies where we have compared background release of the excitatory transmitter, glutamate, and the inhibitory transmitter, GABA, in the two layers, the role of this background release in the balance of excitability, and its control by presynaptic auto- and heteroreceptors on presynaptic terminals.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.