Evidence map›Paper›PMID 15498804›Full record

ReviewThe Journal of physiology2005

Background synaptic activity in rat entorhinal cortical neurones: differential control of transmitter release by presynaptic receptors.

Roland S G Jones, Gavin L Woodhall

Open access · greenAbstract readReview
In one paragraph

Review in The Journal of physiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.1field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Activity-dependent changes in excitability of perirhinal cortex networks in vitro.Pflugers Archiv : European journal of physiology · 2015
    Article
  4. Article
  5. Article
  6. Article
  7. All layers of medial entorhinal cortex receive presubicular and parasubicular inputs.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012
    Article
  8. Review
  9. Article
  10. Artificial synaptic conductances reduce subthreshold oscillations and periodic firing in stellate cells of the entorhinal cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2008
    Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Roland S G JonesDepartment of Pharmacology, University of Bath, Claverton Down, Bath BA2 7AY, UK. r.s.g.jones@bath.ac.uk
Gavin L Woodhall
Aston University · GBUniversity of Bath · GB

Funding

Wellcome Trust 067472
6 · The paper itself

Abstract

The entorhinal cortex (EC) is a key brain area controlling both hippocampal input and output via neurones in layer II and layer V, respectively. It is also a pivotal area in the generation and propagation of epilepsies involving the temporal lobe. We have previously shown that within the network of the EC, neurones in layer V are subject to powerful synaptic excitation but weak inhibition, whereas the reverse is true in layer II. The deep layers are also highly susceptible to acutely provoked epileptogenesis. Considerable evidence now points to a role of spontaneous background synaptic activity in control of neuronal, and hence network, excitability. In the present article we describe results of studies where we have compared background release of the excitatory transmitter, glutamate, and the inhibitory transmitter, GABA, in the two layers, the role of this background release in the balance of excitability, and its control by presynaptic auto- and heteroreceptors on presynaptic terminals.

Indexed as

AnimalsElectrophysiologyEntorhinal CortexNerve NetNeurotransmitter AgentsRatsReceptors, GlutamateReceptors, PresynapticSynapsesNeurotransmitter AgentsReceptors, GlutamateReceptors, Presynaptic

Identifiers

PMID15498804
PMCPMC1665486
OpenAlexW1502437407

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.