Evidence map›Paper›PMID 15498166›Full record

ArticleEmerging infectious diseases2004

Methicillin-resistant Staphylococcus aureus in Europe, 1999-2002.

Edine W Tiemersma, Stef L A M Bronzwaer, Outi Lyytikäinen, John E Degener, Paul Schrijnemakers, Nienke Bruinsma, Jos Monen, Wolfgang Witte, Hajo Grundman, European Antimicrobial Resistance Surveillance System Participants

Abstract readComparative Study
In one paragraph

Article in Emerging infectious diseases, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 166 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
166citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

166 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Population pharmacokinetics of teicoplanin in children.Antimicrobial agents and chemotherapy · 2014
    Trial
  3. Trial
  4. Phenotypic and Genotypic Analyses of Antimicrobial Resistance Patterns ofThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2026
    Article
  5. Methicillin-resistantCurrent pharmaceutical biotechnology · 2025
    Review
  6. Article
  7. Article
  8. Review
  9. Genetic Characterization of Antibiotic-ResistantAntibiotics (Basel, Switzerland) · 2024
    Article
  10. Article
  11. Article
  12. Prevalence and Molecular Characterization of Methicillin-ResistantJournal of microbiology and biotechnology · 2022
    Article
  13. Article
  14. Microbiology insights · 2022
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review

106 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Edine W TiemersmaNational Institute for Public Health and the Environment, Bilthoven, the Netherlands. edine.tiemersma@rivm.nl
Stef L A M Bronzwaer
Outi Lyytikäinen
John E Degener
Paul Schrijnemakers
Nienke Bruinsma
Jos Monen
Wolfgang Witte
Hajo Grundman
European Antimicrobial Resistance Surveillance System Participants

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We explored the variation in proportions of methicillin-resistant Staphylococcus aureus (MRSA) between and within countries participating in the European Antimicrobial Resistance Surveillance System and temporal trends in its occurrence. This system collects routine antimicrobial susceptibility tests for S. aureus. We examined data collected from January 1999 through December 2002 (50,759 isolates from 495 hospitals in 26 countries). MRSA prevalence varied almost 100-fold, from <1% in northern Europe to >40% in southern and western Europe. MRSA proportions significantly increased in Belgium, Germany, Ireland, the Netherlands, and the United Kingdom, and decreased in Slovenia. Within countries, MRSA proportions varied between hospitals with highest variance in countries with a prevalence of 5% to 20%. The observed trends should stimulate initiatives to control MRSA at national, regional, and hospital levels. The large differences between hospitals indicate that efforts may be most effective at regional and hospital levels.

Indexed as

Methicillin ResistanceEuropeHumansInternational CooperationPopulation SurveillancePrevalenceQuality Assurance, Health CareStaphylococcal InfectionsStaphylococcus aureus

Identifiers

PMID15498166
PMCPMC3320277

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.