SynthesisThe Cochrane database of systematic reviews2004
Antibiotic prophylaxis for hernia repair.
Synthesis in The Cochrane database of systematic reviews, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 6 syntheses or guidelines pooled it, 62 citations in OpenAlex.
- Antibiotic prophylaxis for prevention of postoperative wound infection in adults undergoing open elective inguinal or femoral hernia repair.The Cochrane database of systematic reviews · 2020Pooled it
- Network meta-analysis of antibiotic prophylaxis for prevention of surgical-site infection after groin hernia surgery.The British journal of surgery · 2017Pooled it
- Antibiotic prophylaxis for hernia repair.The Cochrane database of systematic reviews · 2012Pooled it
- Meta-analysis of the effectiveness of prophylactic antibiotics in the prevention of postoperative complications after tension-free hernioplasty.Canadian journal of surgery. Journal canadien de chirurgie · 2012Pooled it
- European Hernia Society guidelines on the treatment of inguinal hernia in adult patients.Hernia : the journal of hernias and abdominal wall surgery · 2009Guideline
- Prophylactic antibiotics for mesh inguinal hernioplasty: a meta-analysis.Annals of surgery · 2007Pooled it
- Prophylactic antibiotic use in elective inguinal hernioplasty in a trauma center.Hernia : the journal of hernias and abdominal wall surgery · 2012Trial
- Total extraperitoneal (TEP) mesh repair of inguinal hernia in the developing world: comparison of low-cost indigenous balloon dissection versus direct telescopic dissection: a prospective randomized controlled study.Surgical endoscopy · 2008Trial
- The role of hernia sac ligation in postoperative pain in patients with elective tension-free indirect inguinal hernia repair: a prospective randomized study.Hernia : the journal of hernias and abdominal wall surgery · 2007Trial
- Identification of mixed anaerobic infections after inguinal hernia repair based on metagenomic next-generation sequencing: A case report.Open medicine (Warsaw, Poland) · 2024Article
- Antibiotic prophylaxis in open inguinal hernia repair: a literature review and summary of current knowledge.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2016Review
- Article
- [Hernia surgery in urology: part 1: inguinal, femoral and umbilical hernias - fundamentals of clinical diagnostics and treatment].Der Urologe. Ausg. A · 2013Review
- Does topical rifampicin reduce the risk of surgical field infection in hernia repair?Ulusal cerrahi dergisi · 2013Article
- Do hernia operations in african international cooperation programmes provide good quality?World journal of surgery · 2012Article
- Current options in inguinal hernia repair in adult patients.Hippokratia · 2011Article
- [Inguinal and femoral hernia repair].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2011Review
- Pathogenesis of implant-associated infection: the role of the host.Seminars in immunopathology · 2011Review
- Factors influencing antibiotic prophylaxis for surgical site infection prevention in general surgery: a review of the literature.Canadian journal of surgery. Journal canadien de chirurgie · 2009Review
- Re-operation due to severe late-onset persisting groin pain following anterior inguinal hernia repair with mesh.Hernia : the journal of hernias and abdominal wall surgery · 2008Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe use of antibiotic prophylaxis for hernia repair is currently a controversial issue given the disparity among study results in this area.
objectivesThe objective of this systematic review was to clarify the effectiveness of antibiotic prophylaxis in reducing postoperative wound infection rates in elective open inguinal hernia repair. SEARCH STRATEGY: Searches in the Cochrane Colorectal Cancer Group specialized register were conducted crossing the terms herni* and inguinal or groin and the terms antimicr* or antibiot* , as free text and MeSH terms. A similar search in Medline (WebSPIRS from Silver Platter, January/1966 to March/2004) and Embase (1976 to December/2003) was conducted using the following terms: #1 antibiotic* or antimicrob* or anti infecti* or antiinfecti*; #2 prophyla* or prevent*; #3 #1 and #2; #4 clean and (surgery or tech* or proced*); #5 herni*; #6 (wound infection) and #4; #7 #3 and (#4 or #5 or #6). Reference lists of the included studies were checked to identify additional studies. SELECTION CRITERIA: Only randomized clinical trials were included. DATA COLLECTION AND ANALYSIS: Eight randomized clinical trials were identified. Three of them used prosthetic material for hernia repair (hernioplasty) whereas the remaining studies did not (herniorraphy). Pooled and subgroup analysis were conducted depending on whether prosthetic material was or not used. A random effects model was used in the analysis. MAIN
resultsThe total number of patients included was 2907 (treatment group: 1421, control group: 1486). Overall infection rates were 2.88% and 4.3% in the prophylaxis and control groups, respectively (OR 0.65, 95%CI 0.35 - 1.21). The subgroup of patients with herniorrhaphy had infection rates of 3.78% and 4.87% in the prophylaxis and control groups, respectively (OR 0.84, 95%CI 0.53 - 1.34). The subgroup of patients with hernioplasty had infection rates of 1.2% and 3,3% in the prophylaxis and control groups, respectively (OR 0.28, 95%CI 0.02 - 3.14). REVIEWERS'
conclusionsBased on the results of this meta-analysis, there was no clear evidence that routine administration of antibiotic prophylaxis for elective inguinal hernia repair reduced infection rates.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.