SynthesisThe Cochrane database of systematic reviews2004
Physical methods for preventing deep vein thrombosis in stroke.
Synthesis in The Cochrane database of systematic reviews, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03068338 (Robotic Sock Technology for Prevention of Deep Vein Thrombosis and Joint Contracture), which is not on this map. Cited by 8 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Robotic Sock Technology for Prevention of Deep Vein Thrombosis and Joint Contracture
Who cites it
8 citing papers in PubMed, 3 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- Physical methods for preventing deep vein thrombosis in stroke.The Cochrane database of systematic reviews · 2010Pooled it
- [European Stroke Organisation 2008 guidelines for managing acute cerebral infarction or transient ischemic attack. Part 1].Der Nervenarzt · 2008Guideline
- Risk-assessment algorithm and recommendations for venous thromboembolism prophylaxis in medical patients.Vascular health and risk management · 2007Pooled it
- Effectiveness of thigh-length graduated compression stockings to reduce the risk of deep vein thrombosis after stroke (CLOTS trial 1): a multicentre, randomised controlled trial.Lancet (London, England) · 2009Trial
- Prophylaxis of Venous Thrombosis in Neurocritical Care Patients: An Evidence-Based Guideline: A Statement for Healthcare Professionals from the Neurocritical Care Society.Neurocritical care · 2016Review
- Management of Deep Vein Thrombosis (DVT) Prophylaxis in Trauma Patients.Bulletin of emergency and trauma · 2016Review
- Current issues in thromboprophylaxis in the elderly.Drugs & aging · 2008Review
- Treatment of massive cerebral infarction.Current neurology and neuroscience reports · 2005Review
Corrections and comments
- Updated by
- Update of
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDeep vein thrombosis (DVT) and resulting pulmonary embolism (PE) are uncommon but important complications of stroke. There is good evidence that anticoagulants can reduce the risk of DVT and PE after stroke, but this benefit is offset by a small but definite risk of serious haemorrhages. Physical methods to prevent DVT and PE (such as compression stockings applied to the legs) are not associated with any bleeding risk and are effective in some categories of medical and surgical patients. We sought to assess their effects in stroke patients.
objectivesTo assess the effectiveness and safety of physical methods of preventing the onset of deep vein thrombosis and fatal or non fatal pulmonary embolism in patients with recent stroke. SEARCH STRATEGY: We searched the Cochrane Stroke Group trials register (last searched June 2003). In addition we searched the following electronic bibliographic databases: Cochrane Central Register of Controlled Trials (The Cochrane Library, Issue 2, 2003), MEDLINE (1966 to June 2003), EMBASE (1980 to June 2003) and CINAHL (1982 to June 2003). The reference lists of all relevant papers were screened for additional trials. SELECTION CRITERIA: Unconfounded randomised controlled trials comparing physical methods for the prevention of DVT with control, in which prophylaxis was started within seven days of the onset of stroke. DATA COLLECTION AND ANALYSIS: Two reviewers independently searched for relevant trials and three others independently checked the results. MAIN
resultsWe identified two small trials which included 123 patients. In one trial of 97 patients, compression stockings were associated with a non significant trend towards a reduction in DVT detected by Doppler ultrasound. In one trial of 26 patients, an intermittent pneumatic compression device was not associated with a significant reduction in DVT detected by 125-I-fibrinogen scanning. Overall, physical methods were not associated with a significant reduction in DVT during the treatment period in survivors (Odds ratio (OR) 0.54, 95% Confidence Interval (CI) 0.18 to 1.57) or death (OR 1.54, 95% CI 0.5 to 4.77). REVIEWERS'
conclusionsThere is insufficient evidence from randomised trials to support the routine use of physical methods for preventing DVT in acute stroke.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.