ArticleWorld journal of surgery2004
Multiple endocrine neoplasia type 1 parathyroid adenoma development over time.
Article in World journal of surgery, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- The optimal surgical treatment for primary hyperparathyroidism in MEN1 patients: a systematic review.World journal of surgery · 2011Pooled it
- Syndromic MEN1 parathyroid adenomas consist of both subclonal nodules and clonally independent tumors.Virchows Archiv : an international journal of pathology · 2024Article
- Overview of the 2022 WHO Classification of Familial Endocrine Tumor Syndromes.Endocrine pathology · 2022Review
- Overview of the 2022 WHO Classification of Parathyroid Tumors.Endocrine pathology · 2022Review
- Multiple endocrine neoplasia type 1 (MEN1) presenting with renal stones: Case report and review.Radiology case reports · 2020Article
- Impact of "Tailored" Parathyroidectomy for Treatment of Primary Hyperparathyroidism in Patients with Multiple Endocrine Neoplasia Type 1.World journal of surgery · 2018Article
- Multiple Endocrine Neoplasia Type 1: A Case Report With Review of Imaging Findings.Ochsner journal · 2018Article
- Natural History of MEN1 GEP-NET: Single-Center Experience After a Long Follow-Up.World journal of surgery · 2017Article
- A case of acute confusion: Cushing's syndrome presenting with primary hyperparathyroidism.BMJ case reports · 2017Article
- Multiple Endocrine Neoplasia: A Genetically Diverse Group of Familial Tumor Syndromes.Journal of pediatric genetics · 2016Review
- Primary hyperparathyroidism-jaw tumor syndrome: a confusing and forgotten diagnosis.Clujul medical (1957) · 2016Article
- Ultrasonographic evaluation of parathyroid hyperplasia in multiple endocrine neoplasia type 1: Positive correlation between parathyroid volume and circulating parathyroid hormone concentration.Journal of bone and mineral metabolism · 2015Article
- Article
- Causes and treatment of recurrent hyperparathyroidism after subtotal parathyroidectomy in the presence of multiple endocrine neoplasia 1.World journal of surgery · 2010Article
- Bilateral neck exploration in primary hyperparathyroidism--when is it selected and how is it performed?World journal of surgery · 2009Review
- Surgical approach to the patient with familial hyperparathyroidism.Current treatment options in oncology · 2006Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Multiple gland parathyroid disease is one of the hallmarks of multiple endocrine neoplasia (MEN) type 1. Often mislabeled parathyroid hyperplasia, the process is actually the development of multiple adenomas. Some clinicians have reported results of selective parathyroidectomy in this group, removing only grossly enlarged glands. We argue that all the glands are at risk and should be addressed at any planned parathyroid intervention. Our hypothesis is that, given sufficient time, patients would all develop adenomas in each of the parathyroid glands. Our available data to address this issue are the parathyroidectomy results from a single institution series. Patients who had initial parathyroid exploration for hyperparathyroidism in the setting of MEN-1 were reviewed. This study includes those patients who had the weights of the resected glands documented; 23 men and 21 women met the criteria. The total weight of the parathyroid glands did not vary with the age of the patient at operation. However, the number of normal glands identified did vary significantly with age (p < 0.02), with older patients being less likely to have any normal parathyroid glands. Although total parathyroid weight may correlate with development of hypercalcemia and indications for operation, the involvement of multiple parathyroid glands in MEN-1 is a function of time, as independent events in each gland must occur. Given time, MEN-1 patients all develop multiple gland disease, and this reality must be used in planning operative management for patients with this syndrome.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.