ArticleBiophysical journal2005
Measurements of DNA lengths remaining in a viral capsid after osmotically suppressed partial ejection.
Article in Biophysical journal, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed.
- Cryo-EM and cryo-ET reveal the molecular architecture and host interactions of mycobacteriophage Douge.Cell reports · 2025Article
- AT-specific DNA visualization revisits the directionality of bacteriophage λ DNA ejection.Nucleic acids research · 2023Article
- Single-particle virology.Biophysical reviews · 2020Review
- Article
- Experimental comparison of forces resisting viral DNA packaging and driving DNA ejection.Physical review. E · 2017Article
- A Molecular View of the Dynamics of dsDNA Packing Inside Viral Capsids in the Presence of Ions.Biophysical journal · 2017Article
- Coexistence of coil and globule domains within a single confined DNA chain.Nucleic acids research · 2016Article
- Article
- Ejecting phage DNA against cellular turgor pressure.Biophysical journal · 2014Article
- Molecular architecture of tailed double-stranded DNA phages.Bacteriophage · 2014Review
- DNA ejection from an archaeal virus--a single-molecule approach.Biophysical journal · 2013Article
- DNA bending-induced phase transition of encapsidated genome in phage λ.Nucleic acids research · 2013Article
- Effects of pulling forces, osmotic pressure, condensing agents and viscosity on the thermodynamics and kinetics of DNA ejection from bacteriophages to bacterial cells: a computational study.Journal of physics. Condensed matter : an Institute of Physics journal · 2013Article
- Langevin dynamics simulation of DNA ejection from a phage.Journal of biological physics · 2013Article
- Nucleic acid packaging in viruses.Current opinion in structural biology · 2012Review
- Single-molecule studies of viral DNA packaging.Advances in experimental medicine and biology · 2012Review
- Protein-DNA interactions determine the shapes of DNA toroids condensed in virus capsids.Biophysical journal · 2011Article
- Role of DNA-DNA interactions on the structure and thermodynamics of bacteriophages Lambda and P4.Journal of structural biology · 2011Article
- Ion-dependent dynamics of DNA ejections for bacteriophage lambda.Biophysical journal · 2010Article
- Structure of toroidal DNA collapsed inside the phage capsid.Proceedings of the National Academy of Sciences of the United States of America · 2009Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The effect of external osmotic pressure on the extent of DNA ejection from bacteriophage-lambda was recently investigated (Evilevitch et al., 2003). The total length of DNA ejected was measured via the 260-nm absorption by free nucleotides, after opening of the capsids in the presence of varying amounts of polyethylene glycol 8000 and DNase I. As a function of osmolyte concentration, this absorption was shown to decrease progressively, ultimately vanishing completely for a sufficiently high external osmotic pressure. In this work we report the results of both sedimentation and gel analysis of the length of DNA remaining inside the capsids, as a function of osmolyte concentration. It is confirmed in this way that the progressive inhibition of DNA ejection corresponds to partial ejection from all of the capsids.
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