ReviewJournal of psychiatry & neuroscience : JPN2004
Mother to infant or infant to mother? Reciprocal regulation of responsiveness to stress in rodents and the implications for humans.
Review in Journal of psychiatry & neuroscience : JPN, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed.
- Prenatal and postnatal influences on behavioral development in a mouse model of preconceptional stress.Neurobiology of stress · 2024Article
- Inter- and transgenerational heritability of preconception chronic stress or alcohol exposure: Translational outcomes in brain and behavior.Neurobiology of stress · 2024Article
- Metabolomic and exposomic biomarkers of risk of future neurodevelopmental delay in human milk.Pediatric research · 2023Article
- Maternal dopamine encodes affective signals of human infants.Social cognitive and affective neuroscience · 2022Article
- Less can be more: Fine tuning the maternal brain.Neuroscience and biobehavioral reviews · 2022Review
- Infant Attachment and Social Modification of Stress Neurobiology.Frontiers in systems neuroscience · 2021Review
- Defining Immediate Effects of Sensitive Periods on Infant Neurobehavioral Function.Current opinion in behavioral sciences · 2020Article
- In utero exposure to di(2-ethylhexyl)phthalate suppresses blood glucose and leptin levels in the offspring of wild-type mice.Toxicology · 2019Article
- Antenatal and Postnatal Determinants of Behavioural Difficulties in Early Childhood: Evidence from Growing Up in New Zealand.Child psychiatry and human development · 2019Article
- Adaptive Modifications of Maternal Hypothalamic-Pituitary-Adrenal Axis Activity during Lactation and Salsolinol as a New Player in this Phenomenon.International journal of endocrinology · 2018Review
- Neurobehavioral assessment of maternal odor in developing rat pups: implications for social buffering.Social neuroscience · 2017Article
- Child Odors and Parenting: A Survey Examination of the Role of Odor in Child-Rearing.PloS one · 2016Article
- Mechanisms and functional implications of social buffering in infants: Lessons from animal models.Social neuroscience · 2015Article
- Psychobiological mechanisms underlying the social buffering of the hypothalamic-pituitary-adrenocortical axis: a review of animal models and human studies across development.Psychological bulletin · 2014Review
- Article
- Mother-pup interactions: rodents and humans.Frontiers in endocrinology · 2014Review
- The development and neurobiology of infant attachment and fear.Developmental neuroscience · 2012Review
- Variations in maternal care alter corticosterone and 17beta-estradiol levels, estrous cycle and folliculogenesis and stimulate the expression of estrogen receptors alpha and beta in the ovaries of UCh rats.Reproductive biology and endocrinology : RB&E · 2011Article
- Is cortisol excretion independent of menstrual cycle day? A longitudinal evaluation of first morning urinary specimens.PloS one · 2011Article
- Perceived quality of maternal care in childhood and structure and function of mothers' brain.Developmental science · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Optimal early development in most species is dependent upon a stable relationship between the mother and her infant. The research described here focuses on the reciprocal nature of this dyad in rodents and humans, with respect to the regulation of responsiveness to stress in both mother and offspring. Dietary influences are critical not only to regulate infant growth but also to modulate the response of the neuroendocrine system to stress and, possibly, to influence some aspects of brain development. In particular, we discuss the role of leptin, a protein produced in the adipose tissue and present in maternal milk, that reduces responses to stress in the infant. We suggest that leptin acts on both central (hypothalamus and hippocampus) and peripheral (pituitary, adrenal gland) targets in the infant to reduce exposure to glucocorticoids and enhance hippocampal development during a sensitive period of brain development. There is also evidence to support the reverse regulatory influence, in which maternal state is profoundly affected by stimulation from the young. During the period of lactation, mothers exhibit lower neuroendocrine and behavioural responses to several types of stressors, except possibly those representing a threat to the infant. This ability to "filter" relevant from irrelevant stimuli while caring for their young might be viewed as adaptive for the mother-infant dyad, and the inability to filter adequately stressful stimuli could at least in part be associated with the development of postpartum depression.
Indexed as
Identifiers
15486606PMC518866What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.