ArticleVirchows Archiv : an international journal of pathology2005
Expression of CX3CL1 (fractalkine) in mice with endothelial-target rickettsial infection of the spotted-fever group.
Article in Virchows Archiv : an international journal of pathology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 25 citations in OpenAlex.
- Review
- MicroRNA-424 regulates the expression of CX3CL1 (fractalkine) in human microvascular endothelial cells duringBiochemistry and biophysics reports · 2021Article
- MicroRNA Signature of Human Microvascular Endothelium Infected with Rickettsia rickettsii.International journal of molecular sciences · 2017Article
- Strong type 1, but impaired type 2, immune responses contribute to Orientia tsutsugamushi-induced pathology in mice.PLoS neglected tropical diseases · 2014Article
- Increased expression of the homeostatic chemokines CCL19 and CCL21 in clinical and experimental Rickettsia conorii infection.BMC infectious diseases · 2014Article
- Regulation of inducible heme oxygenase and cyclooxygenase isozymes in a mouse model of spotted fever group rickettsiosis.Microbial pathogenesis · 2012Article
- Infection of the endothelium by members of the order Rickettsiales.Thrombosis and haemostasis · 2009Review
- Host-cell interactions with pathogenic Rickettsia species.Future microbiology · 2009Review
- Emerging and re-emerging rickettsioses: endothelial cell infection and early disease events.Nature reviews. Microbiology · 2008Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Fractalkine (CX3CL1) is a chemokine expressed mainly by endothelial cells, which are the major cellular targets of rickettsiae. We used immunohistochemistry to investigate the normal expression of CX3CL1 in mice and the kinetics of expression of this chemokine throughout the course of lethal and sublethal rickettsial infections in a mouse model of spotted-fever group rickettsioses. The peak of expression of fractalkine on day 3 of infection coincided with the time of infiltration of macrophages into infected tissues and preceded the peak of rickettsial content in tissues.
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