ArticleAnnals of the rheumatic diseases2004
The pustular skin lesions in Behcet's syndrome are not sterile.
Article in Annals of the rheumatic diseases, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 105 citations in OpenAlex.
- Is hidradenitis suppurativa more an autoinfection than pure autoinflammation?Frontiers in immunology · 2026Review
- The association between CD14 (C-159T) single-nucleotide polymorphism and Behcet's syndrome and its clinical manifestations in Egyptian patients, an observational case-control genetic association study.Clinical rheumatology · 2026Observational
- The Role of Viral and Bacterial Infections in the Etiology of Behçet's Disease.Journal of clinical laboratory analysis · 2026Review
- Musculoskeletal manifestations in a cohort of Behçet's disease patients and their impact on health-related quality of life.Internal and emergency medicine · 2025Article
- Enthesitis as an initial presentation of vascular Behçet's syndrome: a case-based review.Rheumatology international · 2024Review
- Heat Shock Proteins in Behçet SyndromeBalkan medical journal · 2023Review
- Article
- Behçet syndrome.Nature reviews. Disease primers · 2021Review
- Succinivibrionaceae is dominant family in fecal microbiota of Behçet's Syndrome patients with uveitis.PloS one · 2020Article
- Understanding Behçet's Disease in the Context of Innate Immunity Activation.Frontiers in immunology · 2020Review
- Triggering agents and microbiome as environmental factors on Behçet's syndrome.Internal and emergency medicine · 2019Review
- Phenotypes in Behçet's syndrome.Internal and emergency medicine · 2019Review
- Immunopathogenesis of Behcet's Disease.Frontiers in immunology · 2019Review
- Labial Pain, Swelling and Fever: An Autoinflammatory Disorder.The American journal of medicine · 2017Article
- Behçet syndrome: from pathogenesis to novel therapies.Clinical and experimental medicine · 2016Review
- Bifidobacteria Abundance-Featured Gut Microbiota Compositional Change in Patients with Behcet's Disease.PloS one · 2016Article
- 'MHC-I-opathy'-unified concept for spondyloarthritis and Behçet disease.Nature reviews. Rheumatology · 2015Review
- The oral mucosal and salivary microbial community of Behçet's syndrome and recurrent aphthous stomatitis.Journal of oral microbiology · 2015Article
- Update on the diagnosis and management of Behçet's disease.Open access rheumatology : research and reviews · 2015Review
- Unmet need in Behcet's disease: most patients in routine follow-up continue to have oral ulcers.Clinical rheumatology · 2014Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe pustular skin lesions of Behcet's syndrome (BS) are clinically and histopathologically similar to ordinary acne, but BS patients get lesions at sites not commonly involved in acne, such as the legs and arms. The microbiology of these lesions has not been studied adequately.
objectiveTo make a detailed study of the microbiology of BS lesions.
methodsSubjects were patients with BS and acne vulgaris. Material was extracted from pustular lesions and directly plated to aerobic and anaerobic media by sterile swab. Anaerobic bacteria were identified using a commercial kit (API 20A). Aerobic bacteria were defined by standard procedures.
results58 BS patients and 37 acne patients were studied. Pustules were cultured from the following sites: BS patients (70 pustules): face (17), back (30), chest (2), arm (4), leg (17); acne patients (37 pustules): face (27), back (6), chest (1), arm (2), leg (1). At least one type of microorganism was grown from each pustule. Staphylococcus aureus (41/70, 58.6%, p = 0.008) and Prevotella spp (17/70, 24.3%, p = 0.002) were significantly more common in pustules from BS patients, and coagulase negative staphylococci (17/37, 45.9%, p = 0.007) in pustules from acne patients.
conclusionsThe pustular lesions of BS are not usually sterile. The microbiology of these lesions is different from ordinary acne. It remains to be determined whether the infection is secondary or has any pathogenic implications.
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