ArticleAnnals of the rheumatic diseases2004
Weight changes and the risk of knee osteoarthritis requiring arthroplasty.
Article in Annals of the rheumatic diseases, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Body mass index and risk of knee osteoarthritis: systematic review and meta-analysis of prospective studies.BMJ open · 2015Pooled it
- Effect of weight reduction in obese patients diagnosed with knee osteoarthritis: a systematic review and meta-analysis.Annals of the rheumatic diseases · 2007Pooled it
- Radiographs and low field MRI (0.2T) as predictors of efficacy in a weight loss trial in obese women with knee osteoarthritis.BMC musculoskeletal disorders · 2011Trial
- Weight change patterns across adulthood are associated with the risk of osteoarthritis: a population-based study.Aging clinical and experimental research · 2024Article
- Association of Weight Loss and Weight Gain With Structural Defects and Pain in Hand Osteoarthritis: Data From the Osteoarthritis Initiative.Arthritis care & research · 2024Article
- Nationwide Cross-Sectional Study of the Association between Knee Pain and Weight Change: Analysis of the Korea National Health and Nutrition Examination Survey (KNHANES 2013-2015).International journal of environmental research and public health · 2021Article
- Article
- Association of weight change with progression of meniscal intrasubstance degeneration over 48 months: Data from the Osteoarthritis Initiative.European radiology · 2018Article
- Association of Metabolic Markers with self-reported osteoarthritis among middle-aged BMI-defined non-obese individuals: a cross-sectional study.BMC obesity · 2018Article
- Strategies for the prevention of knee osteoarthritis.Nature reviews. Rheumatology · 2016Review
- Association of cartilage degeneration with four year weight gain--3T MRI data from the Osteoarthritis Initiative.Osteoarthritis and cartilage · 2015Observational
- Tackling obesity in knee osteoarthritis.Nature reviews. Rheumatology · 2013Review
- Life course body mass index and risk of knee osteoarthritis at the age of 53 years: evidence from the 1946 British birth cohort study.Annals of the rheumatic diseases · 2012Article
- Association between obesity history and hand grip strength in older adults--exploring the roles of inflammation and insulin resistance as mediating factors.The journals of gerontology. Series A, Biological sciences and medical sciences · 2011Article
- Most patients gain weight in the 2 years after total knee arthroplasty: comparison to a healthy control group.Osteoarthritis and cartilage · 2010Article
- [Obesity and arthritis].Der Orthopade · 2005Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo examine the effect of weight changes between 20 and 50 years of age on the risk of severe knee osteoarthritis (OA) requiring arthroplasty. SUBJECTS AND
methodsCases were 55-75 year old men and women (n = 220) having had knee arthroplasty for primary osteoarthritis at the Kuopio University Hospital in 1992-93. Controls (n = 415) were randomly selected from the population of Kuopio Province. Weight at the age of 20, 30, 40, and 50 years was collected retrospectively with a postal questionnaire.
resultsAfter adjustment for age, sex, history of physical workload, recreational physical activity, and previous knee injury, weight gain resulting to a shift from normal body mass index (BMI < or =25 kg/m(2)) to overweight (BMI >25 kg/m(2)) was associated with a higher relative risk of knee OA requiring arthroplasty than persistent overweight from 20-50 years of age, compared with those with normal relative weight during the corresponding age period. The odds ratios (OR) were 3.07 (95% confidence interval 1.87 to 5.05) for those with normal weight at the age of 20 years and overweight at two or three of the ages 30, 40 or 50 years, 3.15 (1.85 to 5.36) for those with overweight from the age of 30 years, and 2.37 (1.21 to 4.62) for those with overweight from the age of 20 years, respectively.
conclusionIn adult life, a shift from normal to overweight may carry a higher risk for knee OA requiring arthroplasty than does constant overweight.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.