Importance of anti- and pro-nociceptive mechanisms in human disease.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

17 citing papers in PubMed.

1. The periaqueductal gray and Bayesian integration in placebo analgesia.eLife · 2018
   Trial
2. Hemorphins, atypical endogenous opiate peptides, in sickle cell disease and their association with pain.Pain · 2026
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3. Mechanical and thermal thresholds before and after application of a conditioning stimulus in healthy Göttingen Minipigs.PloS one · 2024
   Article
4. The role of expectations, control and reward in the development of pain persistence based on a unified model.eLife · 2023
   Review
5. Comorbidity of Alcohol Use Disorder and Chronic Pain: Genetic Influences on Brain Reward and Stress Systems.Alcoholism, clinical and experimental research · 2017
   Review
6. Analgesic effects and pharmacologic mechanisms of the Gelsemium alkaloid koumine on a rat model of postoperative pain.Scientific reports · 2017
   Article
7. Cross-cultural adaptation and validity of the Spanish central sensitization inventory.SpringerPlus · 2016
   Article
8. The important role of CNS facilitation and inhibition for chronic pain.International journal of clinical rheumatology · 2013
   Article
9. Pain processing in patients with migraine: an event-related fMRI study during trigeminal nociceptive stimulation.Journal of neurology · 2012
   Article
10. Does acupuncture therapy alter activation of neural pathway for pain perception in irritable bowel syndrome?: a comparative study of true and sham acupuncture using functional magnetic resonance imaging.Journal of neurogastroenterology and motility · 2012
    Article
11. Abnormal endogenous pain modulation is a shared characteristic of many chronic pain conditions.Expert review of neurotherapeutics · 2012
    Review
12. Evidence for shared pain mechanisms in osteoarthritis, low back pain, and fibromyalgia.Current rheumatology reports · 2011
    Review
13. Interictal cortical reorganization in episodic migraine without aura: an event-related fMRI study during parametric trigeminal nociceptive stimulation.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2011
    Article
14. Central sensitivity syndromes: mounting pathophysiologic evidence to link fibromyalgia with other common chronic pain disorders.Pain management nursing : official journal of the American Society of Pain Management Nurses · 2011
    Review
15. Central processing of noxious somatic stimuli in patients with irritable bowel syndrome compared with healthy controls.The Clinical journal of pain · 2010
    Article
16. Pain and inflammatory bowel disease.Inflammatory bowel diseases · 2009
    Review
17. From nociception to pain perception: imaging the spinal and supraspinal pathways.Journal of anatomy · 2005
    Review

Corrections and comments

• Comment on
  Brain functional magnetic resonance imaging of rectal pain and activation of endogenous inhibitory mechanisms in irritable bowel syndrome patient subgroups and healthy controls.2004

Authors and funding

2 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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