Evidence map›Paper›PMID 15472346›Full record

ArticleJournal of clinical microbiology2004

Use of lung resection and voriconazole for successful treatment of invasive pulmonary Aspergillus ustus infection.

A Azzola, J R Passweg, J M Habicht, L Bubendorf, M Tamm, A Gratwohl, G Eich

Open access · greenAbstract readCase Reports
In one paragraph

Article in Journal of clinical microbiology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
  2. Drug-ResistantPathogens (Basel, Switzerland) · 2023
    Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Voriconazole in the management of nosocomial invasive fungal infections.Therapeutics and clinical risk management · 2006
    Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

A AzzolaDivision of Hematology, Department of Internal Medicine, University Hospital Basel, Basel, Switzerland. AzzolaA@uhbs.ch
J R Passweg
J M Habicht
L Bubendorf
M Tamm
A Gratwohl
G Eich
Respiratory Clinical Trials · AUOffice of Infectious Diseases · USUniversity Hospital of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Invasive pulmonary aspergillosis (IPA) is a common infection in neutropenic patients and is associated with high mortality. Aspergillus ustus is a species that has only rarely been implicated in human disease. All reported cases of IPA due to A. ustus have been fatal. Here, we describe a case of invasive pulmonary A. ustus infection successfully treated with lung resection and voriconazole. A 43-year-old man with acute myeloid leukemia underwent two courses of chemotherapy and experienced prolonged neutropenia. Treatment with amphotericin B was given for persistent fever. While he was receiving amphotericin B, a progressive opacity developed in the upper right lobe. Lung tissue obtained through pulmonary wedge resection for histology showed a mold with septate hyphae, consistent with IPA due to Aspergillus. A. ustus was grown in culture. The patient was then treated with voriconazole and remained in remission of the mold infection in spite of additional chemotherapy and a leukemic relapse. In summary, this report describes the successful treatment of invasive pulmonary A. ustus infection by lung resection and antifungal treatment with voriconazole in a neutropenic patient.

Indexed as

AspergillosisLung Diseases, FungalAdultAntifungal AgentsAspergillusHumansMalePneumonectomyPyrimidinesTreatment OutcomeTriazolesVoriconazoleAntifungal AgentsPyrimidinesTriazolesVoriconazole

Identifiers

PMID15472346
PMCPMC522287
OpenAlexW2152282848

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.