ArticleJournal of molecular evolution2004
Presequence acquisition during secondary endocytobiosis and the possible role of introns.
Article in Journal of molecular evolution, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 48 citations in OpenAlex.
- ASAFind 2.0: multi-class protein targeting prediction for diatoms and algae with complex plastids.The Plant journal : for cell and molecular biology · 2025Article
- Article
- A metabolic, phylogenomic and environmental atlas of diatom plastid transporters from the model speciesFrontiers in plant science · 2022Article
- A Review of Diatom Lipid Droplets.Biology · 2020Review
- Intracellular metabolic pathway distribution in diatoms and tools for genome-enabled experimental diatom research.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2017Review
- Genome-Scale Model Reveals Metabolic Basis of Biomass Partitioning in a Model Diatom.PloS one · 2016Article
- Plastid proteome prediction for diatoms and other algae with secondary plastids of the red lineage.The Plant journal : for cell and molecular biology · 2015Article
- Evidence for the retention of two evolutionary distinct plastids in dinoflagellates with diatom endosymbionts.Genome biology and evolution · 2014Article
- Serial gene losses and foreign DNA underlie size and sequence variation in the plastid genomes of diatoms.Genome biology and evolution · 2014Article
- A novel type of light-harvesting antenna protein of red algal origin in algae with secondary plastids.BMC evolutionary biology · 2013Article
- The falsifiability of the models for the origin of eukaryotes.Current genetics · 2011Review
- The physical and functional borders of transit peptide-like sequences in secondary endosymbionts.BMC plant biology · 2010Article
- A possible role for short introns in the acquisition of stroma-targeting peptides in the flagellate Euglena gracilis.DNA research : an international journal for rapid publication of reports on genes and genomes · 2010Article
- Filling the gap, evolutionarily conserved Omp85 in plastids of chromalveolates.The Journal of biological chemistry · 2010Article
- Molecular characterization of the Calvin cycle enzyme phosphoribulokinase in the stramenopile alga Vaucheria litorea and the plastid hosting mollusc Elysia chlorotica.Molecular plant · 2009Article
- On the origin of chloroplasts, import mechanisms of chloroplast-targeted proteins, and loss of photosynthetic ability - review.Folia microbiologica · 2009Review
- Protein targeting into complex diatom plastids: functional characterisation of a specific targeting motif.Plant molecular biology · 2007Article
- Analysis of Euglena gracilis plastid-targeted proteins reveals different classes of transit sequences.Eukaryotic cell · 2006Article
- Protein targeting into the complex plastid of cryptophytes.Journal of molecular evolution · 2006Article
- The peculiar distribution of class I and class II aldolases in diatoms and in red algae.Current genetics · 2005Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Targeting of nucleus-encoded proteins into chloroplasts is mediated by N-terminal presequences. During evolution of plastids from formerly free-living cyanobacteria by endocytobiosis, genes for most plastid proteins have been transferred from the plastid genome to the nucleus and subsequently had to be equipped with such plastid targeting sequences. So far it is unclear how the gene domains coding for presequences and the respective mature proteins may have been assembled. While land plant plastids are supposed to originate from a primary endocytobiosis event (a prokaryotic cyanobacterium was taken up by a eukaryotic cell), organisms with secondary plastids like diatoms experienced a second endocytobiosis step involving a eukaryotic alga taken up by a eukaryotic host cell. In this group of algae, apparently most genes encoding chloroplast proteins have been transferred a second time (from the nucleus of the endosymbiont to the nucleus of the secondary host) and thus must have been equipped with additional targeting signals. We have analyzed cDNAs and the respective genomic DNA fragments of seven plastid preproteins from the diatom Phaeodactylum tricornutum. In all of these genes we found single spliceosomal introns, generally located within the region coding for the N-terminal plastid targeting sequences or shortly downstream of it. The positions of the introns can be related to the putative phylogenetic histories of the respective genes, indicating that the bipartite targeting sequences in these secondary algae might have evolved by recombination events via introns.
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