ArticleSexually transmitted infections2004
Investigating ethnic inequalities in the incidence of sexually transmitted infections: mathematical modelling study.
Article in Sexually transmitted infections, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- Simulation models for socioeconomic inequalities in health: a systematic review.International journal of environmental research and public health · 2013Pooled it
- The potential impact of a vaccine on Neisseria gonorrhoeae prevalence among heterosexuals living in a high prevalence setting.Vaccine · 2023Article
- Ethnic variations in sexual partnerships and mixing, and their association with STI diagnosis: findings from a cross-sectional biobehavioural survey of attendees of sexual health clinics across England.Sexually transmitted infections · 2020Article
- A dynamic power-law sexual network model of gonorrhoea outbreaks.PLoS computational biology · 2019Article
- Estimated Impact of Screening on Gonorrhea Epidemiology in the United States: Insights From a Mathematical Model.Sexually transmitted diseases · 2018Article
- Ethnicity and sexual risk in heterosexual people attending sexual health clinics in England: a cross-sectional, self-administered questionnaire study.Sexually transmitted infections · 2018Article
- It's the network, stupid: a population's sexual network connectivity determines its STI prevalence.F1000Research · 2018Article
- Epidemiological, behavioural, and clinical factors associated with antimicrobial-resistant gonorrhoea: a review.F1000Research · 2018Review
- A protocol for a cluster randomised feasibility study of an adolescent incentive intervention to increase uptake of HPV vaccination among girls.Pilot and feasibility studies · 2017Article
- Patterns of sexual mixing with respect to social, health and sexual characteristics among heterosexual couples in England: analyses of probability sample survey data.Epidemiology and infection · 2015Article
- Cross-cultural differences and sexual risk behavior of emerging adults.Journal of transcultural nursing : official journal of the Transcultural Nursing Society · 2015Article
- Who mixes with whom among men who have sex with men? Implications for modelling the HIV epidemic in southern India.Journal of theoretical biology · 2014Article
- Racial disparities in HIV prevalence and risk behaviors among injection drug users and members of their risk networks.Journal of acquired immune deficiency syndromes (1999) · 2013Article
- Racial/ethnic and sexual behavior disparities in rates of sexually transmitted infections, San Francisco, 1999-2008.BMC public health · 2010Article
- A Bayesian approach to uncertainty analysis of sexually transmitted infection models.Sexually transmitted infections · 2010Article
- A metapopulation modelling framework for gonorrhoea and other sexually transmitted infections in heterosexual populations.Journal of the Royal Society, Interface · 2009Article
- The role of compensatory mutations in the emergence of drug resistance.PLoS computational biology · 2006Article
- Marijuana use and sexually transmitted infections in young women who were teenage mothers.Women's health issues : official publication of the Jacobs Institute of Women's HealthArticle
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo investigate ethnic differences in rates of gonorrhoea using empirical sexual behaviour data in a simple mathematical model. To explore the impact of different intervention strategies in this simulated population.
methodsThe findings from cross sectional studies of gonorrhoea rates and sexual behaviour in three ethnic groups in south east London were used to determine the parameters for a deterministic, mathematical model of gonorrhoea transmission dynamics, in a population stratified by sex, sexual activity (rate of partner change), and ethnic group (white, black African, and black Caribbean). We compared predicted and observed rates of infection and simulated the effects of targeted and population-wide intervention strategies.
resultsIn model simulations the reported sexual behaviours and mixing patterns generated major differences in the rates of gonorrhoea experienced by each subpopulation. The fit of the model to observed data was sensitive to assumptions about the degree of mixing by level of sexual activity, the numbers of sexual partnerships reported by men and women, and the degree to which observed data underestimate female infection rates. Interventions to reduce duration of infection were most effective when targeted at black Caribbeans.
conclusionsAverage measures of sexual behaviour in large populations are inadequate descriptors for the epidemiology of gonorrhoea. The consistency between the model results and empirical data shows that profound differences in gonorrhoea rates between ethnic groups can be explained by modest differences in a limited number of sexual behaviours and mixing patterns. Targeting effective services to particular ethnic groups can have a disproportionate influence on disease reduction in the whole community.
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