Evidence map›Paper›PMID 15459400›Full record

Trial reportSexually transmitted infections2004

The chlamydia screening studies: rationale and design.

N Low, A McCarthy, J Macleod, C Salisbury, P J Horner, T E Roberts, R Campbell, A Herring, S Skidmore, E Sanford and 6 more

Registry-linked trialAbstract readClinical TrialRandomized Controlled Trial
In one paragraph

Trial report in Sexually transmitted infections, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00112255 (Partner Notification for Chlamydia in Primary Care), which is not on this map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00112255 phase3completednot on this map

Partner Notification for Chlamydia in Primary Care: Randomised Controlled Trial and Economic Evaluation

TypeinterventionalSponsorUniversity of BristolRan2001 to 2002Enrolled214ConditionsChlamydia InfectionsArmsPractice nurse-led partner notification, Referral to specialist genitourinary clinic
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
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  6. Review
  7. Review
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  11. [Modern diagnosis of Chlamydia trachomatis infections].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2007
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Opportunistic and systematic screening for chlamydia: a study of consultations by young adults in general practice.The British journal of general practice : the journal of the Royal College of General Practitioners · 2006
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors.

N LowDepartment of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK. nicola.low@bristol.ac.uk
A McCarthy
J Macleod
C Salisbury
P J Horner
T E Roberts
R Campbell
A Herring
S Skidmore
E Sanford
J A C Sterne
G Davey Smith
A Graham
M Huengsberg
J Ross
M Egger

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundScreening has been recommended to reduce the prevalence and morbidity associated with genital chlamydia infection in the United Kingdom.

methodsWe describe the rationale and study design of the Chlamydia Screening Studies (ClaSS), a collaborative project designed to evaluate screening outside genitourinary medicine clinics. A non-selective, active screening approach in 16-39 year olds randomly sampled from 27 general practice lists in the Bristol and Birmingham areas formed the basis of interlinked studies: a case-control study was used to investigate factors to improve the targeting of screening; participants with chlamydia were invited to enroll in a randomised controlled trial to evaluate partner notification conducted in primary care; and laboratory based studies were used to assess the best specimens and tests. We also explored psychosocial effects of screening and partner notification and modelled the cost effectiveness of the programme.

conclusionResults from four pilot practices show that mailing of specimens for chlamydia testing is feasible but that it is difficult to achieve high response rates with postal screening. The high prevalence of asymptomatic infection in men suggests that efforts to screen men for chlamydia should be strengthened.

Indexed as

AdolescentAdultAttitude to HealthCase-Control StudiesChlamydia InfectionsContact TracingCross-Sectional StudiesFemaleHumansMaleMass ScreeningMultivariate AnalysisRandomized Controlled Trials as TopicSexual Partners

Identifiers

PMID15459400
PMCPMC1744885

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.