ArticleMolecular genetics and genomics : MGG2004
Genome-scan analysis for quantitative trait loci in an F2 tilapia hybrid.
Article in Molecular genetics and genomics : MGG, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed.
- Sex determination mechanisms and sex control approaches in aquaculture animals.Science China. Life sciences · 2022Review
- First identification of two co-existing genome-wide significant sex quantitative trait loci (QTL) in red tilapia using integrative QTL mapping.Zoological research · 2022Article
- A Chromosome-Level Genome Assembly of Mozambique Tilapia (Frontiers in genetics · 2021Article
- QTL Mapping for Red Blotches in Malaysia Red Tilapia (Oreochromis spp.).Marine biotechnology (New York, N.Y.) · 2019Article
- Review
- High-Density Linkage Map and QTLs for Growth in Snapper (G3 (Bethesda, Md.) · 2019Article
- Marker-assisted selection of YY supermales from a genetically improved farmed tilapia-derived strain.Zoological research · 2019Article
- Construction of a High-Density Linkage Map and QTL Fine Mapping for Growth- and Sex-Related Traits in Channel Catfish (Frontiers in genetics · 2019Article
- Review
- Identifying a Major QTL Associated with Salinity Tolerance in Nile Tilapia Using QTL-Seq.Marine biotechnology (New York, N.Y.) · 2018Article
- Genome-Wide QTL Analysis Identified Significant Associations Between Hypoxia Tolerance and Mutations in the GPR132 and ABCG4 Genes in Nile Tilapia.Marine biotechnology (New York, N.Y.) · 2017Article
- Construction of a high-density linkage map and mapping of sex determination and growth-related loci in the mandarin fish (Siniperca chuatsi).BMC genomics · 2017Article
- Screening and identification of a microsatellite marker associated with sex in Wami tilapia, Oreochromis urolepis hornorum.Journal of genetics · 2016Article
- Signatures of selection in tilapia revealed by whole genome resequencing.Scientific reports · 2015Article
- A genome scan revealed significant associations of growth traits with a major QTL and GHR2 in tilapia.Scientific reports · 2014Article
- Article
- Whole genome scanning and association mapping identified a significant association between growth and a SNP in the IFABP-a gene of the Asian seabass.BMC genomics · 2013Article
- A microsatellite-based linkage map of salt tolerant tilapia (Oreochromis mossambicus x Oreochromis spp.) and mapping of sex-determining loci.BMC genomics · 2013Article
- A high-resolution map of the Nile tilapia genome: a resource for studying cichlids and other percomorphs.BMC genomics · 2012Article
- Linkage and Physical Mapping of Sex Region on LG23 of Nile Tilapia (Oreochromis niloticus).G3 (Bethesda, Md.) · 2012Article
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5 authors.
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Abstract
We searched for genetic linkage between DNA markers and quantitative trait loci (QTLs) for innate immunity, response to stress, biochemical parameters of blood, and fish size in an F2 population derived from an interspecific tilapia hybrid (Oreochromis mossambicusx O. aureus). A family of 114 fish was scanned for 40 polymorphic microsatellite DNA markers and two polymorphic genes, covering approximately 80% of the tilapia genome. These fish had previously been phenotyped for seven immune-response traits and six blood parameters. Critical values for significance were P <0.05 with the false discovery rate (FDR) controlled at 40%. The genome-scan analysis resulted in 35 significant marker-trait associations, involving 26 markers in 16 linkage groups. In a second experiment, nine markers were re-sampled in a second family of 79 fish of the same species hybrid. Seven markers (GM180, GM553, MHC-I, UNH848, UNH868, UNH898 and UNH925) in five linkage groups (LG 1, 3, 4, 22 and 23) were associated with stress response traits. An additional six markers (GM47, GM552, UNH208, UNH881, UNH952, UNH998) in five linkage groups (LG 4, 16, 19, 20 and 23) were verified for their associations with immune response traits, by linkage to several different traits. The portion of variance explained by each QTL was 11% on average, with a maximum of 29%. The average additive effect of QTLs was 0.2 standard deviation units of stress response traits and fish size, with a maximum of 0.33. In three linkage groups (LG 1, 3 and 23) markers were associated with stress response, body weight and sex determination, confirming the location of QTLs reported by several other studies.
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