Evidence map›Paper›PMID 15448904›Full record

ReviewDer Urologe. Ausg. A2004

[Acellular matrix for functional reconstruction of the urogenital tract. Special form of "tissue engineering"?].

N Schlote, J Wefer, K-D Sievert

Abstract readEnglish AbstractReview
PubMed Publisher
In one paragraph

Review in Der Urologe. Ausg. A, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

N SchloteKlinik und Poliklinik für Urologie und Kinderurologie, Medizinische Hochschule, Hannover. schlote.norbert@mh-hannover.de
J Wefer
K-D Sievert
Klinik und Poliklinik für Urologie · DEMedizinische Hochschule Hannover · DEUniversity of Tübingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Organ substitution and reconstruction of the urogenital system still poses a problem regarding an adequate substitute. Usually non-organ-specific materials are used for reconstruction (bowl, buccal mucosa). This nonspecific tissue can cause side effects that result from the origin and the natural function. Different groups have shown that an acellular matrix graft in the urinary bladder and the urethra served as a scaffold for complete regeneration of all organ wall components and that this organ-specific regeneration simultaneously facilitates functional restitution. New approaches will presumably effect better regeneration after seeding the matrix with organ-specific cells (i.e., urothelial cells). Smaller studies on genital reconstructive surgery could show that vaginal substitution with an acellular matrix might be possible or that there could be a possible substitute for the tunica during surgical treatment of Peyronie's disease.

Indexed as

Bioartificial OrgansBiocompatible MaterialsExtracellular MatrixMale Urogenital DiseasesAbsorbable ImplantsAnimalsBiomimetic MaterialsCell Culture TechniquesFemale Urogenital DiseasesHumansPlastic Surgery ProceduresRegenerationTissue EngineeringBiocompatible Materials

Identifiers

PMID15448904
OpenAlexW165122252

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.