Evidence map›Paper›PMID 15448891›Full record

ReviewIntensive care medicine2004

Matching total body oxygen consumption and delivery: a crucial objective?

Pierre Squara

Abstract readReview
PubMed Publisher
In one paragraph

Review in Intensive care medicine, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. A new ratio for protocol categorization.Computational and mathematical methods in medicine · 2014
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Pierre SquaraCERIC Clinique Ambroise Pare, 27 Boulevard Victor Hugo, 92200 Neuilly-sur-Seine, France. pierre.squara@wanadoo.fr

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The strength of the rationale for incorporating total body oxygen consumption (VO(2)) and delivery (DO(2)) into our decision making strategies contrasts with the absence of demonstrated benefits of bedside calculations in clinical practice. This situation mandates a careful reappraisal of the theoretical limitations of bedside calculations of DO(2) and VO(2), including a re-evaluation of the clinical situations in which these calculations are valid. Three levels of complexity can be distinguished when analysing a patient's hemodynamic status: 1) simple cases where investigations can be limited to clinical monitoring, including lactate changes over time; 2) intermediate situations requiring invasive investigations in which continuous monitoring of VO(2)-related variables such as cardiac output and mixed venous oxygen saturation often provide enough information to guide clinical decision; and 3) complex situations where assessment of VO(2) and VO(2)/DO(2) analysis might be recommended. Although studies that support such recommendations are limited they are based on a widely accepted physiological model. VO(2) and DO(2) analysis is also limited by theoretical and technical difficulties. In this article, we discuss the validity of these limitations in the bedside assessment of VO(2) and DO(2), and review data supporting the use of VO(2)/DO(2) analysis in the clinical evaluation of complex cases.

Indexed as

Logistic ModelsCardiac OutputCritical CareDecision MakingHumansOxygenOxygen ConsumptionShockOxygen

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.