ReviewBrain pathology (Zurich, Switzerland)2004
Chronic hydrocephalus in adults.
Review in Brain pathology (Zurich, Switzerland), 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 2 syntheses or guidelines pooled it, 110 citations in OpenAlex.
- Age-specific global epidemiology of hydrocephalus: Systematic review, metanalysis and global birth surveillance.PloS one · 2018Pooled it
- Endoscopic third ventriculostomy (ETV) for idiopathic normal pressure hydrocephalus (iNPH).The Cochrane database of systematic reviews · 2015Pooled it
- Arrested hydrocephalus and beyond: advances in the pathophysiology, diagnosis, and management of various forms of chronic hydrocephalus: a comprehensive narrative review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026Review
- Predictors of shunt responsiveness and outcomes in idiopathic normal pressure hydrocephalus: a retrospective cohort study.Acta neurochirurgica · 2026Article
- Safety and feasibility of dual external ventricular and lumbar drainage with rt-PA in intraventricular hemorrhage: A pilot study.Neurosurgical review · 2026Article
- Uncloggable ventriculoperitoneal shunt system for hydrocephalus via an integrated soft robotic device: CLEARS device.Biomedical microdevices · 2025Article
- Acute decompensation of chronic hydrocephalus following elective abdominal surgery presenting as paroxysmal sympathetic hyperactivity: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- A report on three cases of chronic adult hydrocephalus occurring several months postlumbar spine surgery complicated by cerebrospinal fluid leakage.Surgical neurology international · 2025Article
- Impaired cerebrospinal fluid circulation and cerebral lymphatic drainage in a rat model of chronic hydrocephalus.Frontiers in molecular neuroscience · 2025Article
- Optimal trajectory of the neuroendoscope for third ventricle pavement access.Frontiers in neuroanatomy · 2025Article
- A Bidirectional Mendelian Randomization Study of the Causal Association Between Ischemic Stroke, Coronary Heart Disease, and Hydrocephalus.Brain and behavior · 2024Article
- Insights on pathophysiology of hydrocephalus rats induced by kaolin injection.FASEB bioAdvances · 2024Article
- The clinical spectrum and management outcome of adult-onset aqueductal stenosis: Insight from South-West Nigeria.Surgical neurology international · 2024Article
- Brain blood flow pulse analysis may help to recognize individuals who suffer from hydrocephalus.Acta neurochirurgica · 2023Article
- Congenital hydrocephalus diagnosed in a nonagenarian: Case report.The neuroradiology journal · 2023Article
- Papez circuit change following ventriculoperitoneal shunt for hydrocephalus: a case report.Acta neurologica Belgica · 2022Article
- Comorbid alpha synucleinopathies in idiopathic normal pressure hydrocephalus.Journal of neurology · 2022Article
- Impacts of the COVID-19 Pandemic on the Healthcare Provision and Lived Experiences of Patients with Hydrocephalus.Journal of patient experience · 2022Article
- Molecular Mechanisms and Risk Factors for the Pathogenesis of Hydrocephalus.Frontiers in genetics · 2021Review
- Changing the paradigm of intracranial hypertension in brain tumor patients: a study based on non-invasive ICP measurements.BMC neurology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic hydrocephalus is a complex condition, the incidence of which increases with increasing age. It is characterised by the presence of ventricular enlargement in the absence of significant elevations of intracranial pressure. The clinical syndrome may develop either as a result of decompensation of a "compensated" congenital hydrocephalus, or it may arise de novo in adult life secondary to a known acquired disturbance of normal CSF dynamics. The latter may be due to late onset acqueductal stenosis or disruption of normal CSF absorptive pathways following subarachnoid hemorrhage or meningitis ("secondary" normal pressure hydrocephalus (NPH)). In some cases the cause of the hydrocephalus remains obscure ("idiopathic" NPH). In all forms of chronic hydrocephalus the clinical course of the disease is heavily influenced by changes in the brain associated with aging, in particular cerebrovascular disease. Recent research has challenged previously held tenets regarding the CSF circulatory system and this in turn has led to a radical rethinking of the pathophysiological basis of chronic hydrocephalus.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.