ArticleMammalian genome : official journal of the International Mammalian Genome Society1992
A linkage map of mouse chromosome 1 using an interspecific cross segregating for the gld autoimmunity mutation.
Article in Mammalian genome : official journal of the International Mammalian Genome Society, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 85 citations in OpenAlex.
- Mouse Genome Informatics (MGI) Resource: Genetic, Genomic, and Biological Knowledgebase for the Laboratory Mouse.ILAR journal · 2017Review
- Effects of low-dose-gamma rays on the immune system of different animal models of disease.Dose-response : a publication of International Hormesis Society · 2014Article
- Marked mitigation of transplant vascular sclerosis in FasLgld (CD95L) mutant recipients. The role of alloantibodies in the development of chronic rejection.Transplantation · 1999Article
- Molecular characterization of a mouse genomic element mobilized by advanced glycation endproduct modified-DNA (AGE-DNA).Molecular medicine (Cambridge, Mass.) · 1997Article
- Mapping of the calcium-sensing receptor gene (CASR) to human chromosome 3q13.3-21 by fluorescence in situ hybridization, and localization to rat chromosome 11 and mouse chromosome 16.Mammalian genome : official journal of the International Mammalian Genome Society · 1995Article
- Cloning, structural analysis and mapping of the mouse selenocysteine tRNA([Ser]Sec) gene (Trsp).Molecular & general genetics : MGG · 1995Article
- Low resolution mapping around the flavivirus resistance locus (Flv) on mouse chromosome 5.Mammalian genome : official journal of the International Mammalian Genome Society · 1995Article
- The gene encoding the mouse serum amyloid A protein, apo-SAA5, maps to proximal chromosome 7.Immunogenetics · 1995Article
- Physical and genetic linkage of the genes encoding Ly-9 and CD48 on mouse and human chromosomes 1.Immunogenetics · 1995Article
- Mapping of the genes for four members of the transmembrane 4 superfamily: mouse Cd9, Cd63, Cd81, and Cd82.Immunogenetics · 1995Article
- Rapid and efficient construction of yeast artificial chromosome contigs in the mouse genome with interspersed repetitive sequence PCR (IRS-PCR): generation of a 5-cM, > 5 megabase contig on mouse chromosome 1.Mammalian genome : official journal of the International Mammalian Genome Society · 1994Article
- Molecular characterization of murine and human OX40/OX40 ligand systems: identification of a human OX40 ligand as the HTLV-1-regulated protein gp34.The EMBO journal · 1994Article
- Mapping of PCR-based markers for mouse chromosome 4 on a backcross penetrant for the misty (m) mutation.Mammalian genome : official journal of the International Mammalian Genome Society · 1994Article
- Glycogen synthase: a putative locus for diet-induced hyperglycemia.The Journal of clinical investigation · 1994Article
- Localization of the osteocalcin gene cluster on mouse chromosome 3.Mammalian genome : official journal of the International Mammalian Genome Society · 1994Article
- The role of nitric oxide in the pathogenesis of spontaneous murine autoimmune disease: increased nitric oxide production and nitric oxide synthase expression in MRL-lpr/lpr mice, and reduction of spontaneous glomerulonephritis and arthritis by orally administered NG-monomethyl-L-arginine.The Journal of experimental medicine · 1994Article
- Single-strand conformation polymorphism (SSCP) analysis as a tool for genetic mapping.Mammalian genome : official journal of the International Mammalian Genome Society · 1993Review
- Linking yeast genetics to mammalian genomes: identification and mapping of the human homolog of CDC27 via the expressed sequence tag (EST) data base.Proceedings of the National Academy of Sciences of the United States of America · 1993Article
- Chromosomal localization of glutamate receptor genes: relationship to familial amyotrophic lateral sclerosis and other neurological disorders of mice and humans.Proceedings of the National Academy of Sciences of the United States of America · 1993Article
- The functional genes for protein synthesis initiation factor 4AI and 4AII map to mouse chromosomes 11 and 16.Mammalian genome : official journal of the International Mammalian Genome Society · 1993Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
Abstract
An interspecific backcross was used to define a high resolution linkage map of mouse Chromosome (Chr) 1 and to analyze the segregation of the generalized lymphoproliferative disease (gld) mutation. Mice homozygous for gld have multiple features of autoimmune disease. Analysis of up to 428 progeny from the backcross [(C3H/HeJ-gld x Mus spretus)F1 x C3H/HeJ-gld] established a map that spans 77.6 cM and includes 56 markers distributed over 34 ordered genetic loci. The gld mutation was mapped to a less than 1 cM segment on distal mouse Chr 1 using 357 gld phenotype-positive backcross mice. A second backcross, between the laboratory strains C57BL/6J and SWR/J, was examined to compare recombination frequency between selected markers on mouse Chr 1. Significant differences in crossover frequency were demonstrated between the interspecific backcross and the inbred laboratory cross for the entire interval studied. Sex difference in meiotic crossover frequency was also significant in the laboratory mouse cross. Two linkage groups known to be conserved between segments of mouse Chr 1 and the long arm of human Chrs 1 and 2 where further defined and a new conserved linkage group was identified that includes markers of distal mouse Chr 1 and human Chr 1, bands q32 to q42.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.