ArticleRNA (New York, N.Y.)2004
Cbf5p, the putative pseudouridine synthase of H/ACA-type snoRNPs, can form a complex with Gar1p and Nop10p in absence of Nhp2p and box H/ACA snoRNAs.
Article in RNA (New York, N.Y.), 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
23 citing papers in PubMed, 54 citations in OpenAlex.
- Northern Blotting: Protocols for Radioactive and Nonradioactive Detection of RNA.Methods in molecular biology (Clifton, N.J.) · 2025Article
- The presence of the ACA box in archaeal H/ACA guide RNAs promotes atypical pseudouridylation.RNA (New York, N.Y.) · 2020Article
- Human intron-encoded AluACA RNAs and telomerase RNA share a common element promoting RNA accumulation.RNA biology · 2016Article
- RNA-guided isomerization of uridine to pseudouridine--pseudouridylation.RNA biology · 2014Review
- Interactome analysis reveals versatile functions of Arabidopsis COLD SHOCK DOMAIN PROTEIN 3 in RNA processing within the nucleus and cytoplasm.Cell stress & chaperones · 2013Article
- Human intron-encoded Alu RNAs are processed and packaged into Wdr79-associated nucleoplasmic box H/ACA RNPs.Genes & development · 2012Article
- Reconstitution and structural analysis of the yeast box H/ACA RNA-guided pseudouridine synthase.Genes & development · 2011Article
- Structure of H/ACA RNP protein Nhp2p reveals cis/trans isomerization of a conserved proline at the RNA and Nop10 binding interface.Journal of molecular biology · 2011Article
- Dyskeratosis congenita mutations in the H/ACA domain of human telomerase RNA affect its assembly into a pre-RNP.RNA (New York, N.Y.) · 2009Article
- Genetic heterogeneity in autosomal recessive dyskeratosis congenita with one subtype due to mutations in the telomerase-associated protein NOP10.Human molecular genetics · 2007Article
- H/ACA small nucleolar RNA pseudouridylation pockets bind substrate RNA to form three-way junctions that position the target U for modification.Proceedings of the National Academy of Sciences of the United States of America · 2007Article
- The structure and function of small nucleolar ribonucleoproteins.Nucleic acids research · 2007Review
- Analysis of the binding of the N-terminal conserved domain of yeast Cbf5p to a box H/ACA snoRNA.RNA (New York, N.Y.) · 2006Article
- How a single protein complex accommodates many different H/ACA RNAs.Trends in biochemical sciences · 2006Review
- Stepwise RNP assembly at the site of H/ACA RNA transcription in human cells.The Journal of cell biology · 2006Article
- Structural study of the H/ACA snoRNP components Nop10p and the 3' hairpin of U65 snoRNA.RNA (New York, N.Y.) · 2006Article
- Dyskeratosis congenita: a disorder of defective telomere maintenance?International journal of hematology · 2005Review
- The cotranscriptional assembly of snoRNPs controls the biosynthesis of H/ACA snoRNAs in Saccharomyces cerevisiae.Molecular and cellular biology · 2005Article
- RNA-guided RNA modification: functional organization of the archaeal H/ACA RNP.Genes & development · 2005Article
- The many facets of H/ACA ribonucleoproteins.Chromosoma · 2005Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Box C/D and box H/ACA small ribonucleoprotein particles (sRNPs) are found from archaea to humans, and some of these play key roles during the biogenesis of ribosomes or components of the splicing apparatus. The protein composition of the core of both types of particles is well established and the assembly pathway of box C/D sRNPs has been extensively investigated both in archaeal and eukaryotic systems. In contrast, knowledge concerning the mode of assembly and final structure of box H/ACA sRNPs is much more limited. In the present study, we have investigated the protein/protein interactions taking place between the four protein components of yeast box H/ACA small nucleolar RNPs (snoRNPs), Cbf5p, Gar1p, Nhp2p, and Nop10p. We provide evidence that Cbf5p, Gar1p, and Nop10p can form a complex devoid of Nhp2p and small nucleolar RNA (snoRNA) components of the particles and that Cbf5p and Nop10p can directly bind to each other. We also show that the absence of any component necessary for assembly of box H/ACA snoRNPs inhibits accumulation of Cbf5p, Gar1p, or Nop10p, whereas Nhp2p levels are little affected.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.