ArticleThe Journal of physiology2004
Carotid baroreflex control of leg vasculature in exercising and non-exercising skeletal muscle in humans.
Article in The Journal of physiology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 50 citations in OpenAlex.
- Influence of a neck compression collar on cerebrovascular and autonomic function in men and women.PloS one · 2019Trial
- Muscle oxygenation profiles between active and inactive muscles with nitrate supplementation under hypoxic exercise.Physiological reports · 2017Trial
- Sex differences in carotid baroreflex control of arterial blood pressure in humans: relative contribution of cardiac output and total vascular conductance.American journal of physiology. Heart and circulatory physiology · 2011Trial
- Inhibition of KATP channel activity augments baroreflex-mediated vasoconstriction in exercising human skeletal muscle.The Journal of physiology · 2004Trial
- Systemic cardiovascular and carotid baroreflex support of arterial pressure during recovery from passive heat stress in young and older adults.Physiological reports · 2025Article
- A critical assessment of sympathetic restraint in submaximal exercise: Implications for integrated cardiovascular circuit control in exercise.Experimental physiology · 2025Review
- Passive leg movement-induced vasodilation and exercise-induced sympathetic vasoconstriction.Autonomic neuroscience : basic & clinical · 2022Article
- Baroreceptor Modulation of the Cardiovascular System, Pain, Consciousness, and Cognition.Comprehensive Physiology · 2021Article
- Type 2 diabetes and reduced exercise tolerance: a review of the literature through an integrated physiology approach.Cardiovascular diabetology · 2020Review
- Augmented resting beat-to-beat blood pressure variability in young, healthy, non-Hispanic black men.Experimental physiology · 2020Article
- Muscle sympathetic nerve activity during exercise.The journal of physiological sciences : JPS · 2019Review
- Impact of 60 days of 6° head down tilt bed rest on muscular oxygen uptake and heart rate kinetics: efficacy of a reactive sledge jump countermeasure.European journal of applied physiology · 2018Article
- Exercise intolerance in Type 2 diabetes: is there a cardiovascular contribution?Journal of applied physiology (Bethesda, Md. : 1985) · 2018Review
- Rapid onset pressor and sympathetic responses to static handgrip in older hypertensive adults.Journal of human hypertension · 2015Article
- Cardiovascular Reflexes Activity and Their Interaction during Exercise.BioMed research international · 2015Review
- Blood pressure regulation II: what happens when one system must serve two masters--oxygen delivery and pressure regulation?European journal of applied physiology · 2014Review
- Persistence of functional sympatholysis post-exercise in human skeletal muscle.Frontiers in physiology · 2013Article
- Human investigations into the arterial and cardiopulmonary baroreflexes during exercise.Experimental physiology · 2012Review
- The functional role of the alpha-1 adrenergic receptors in cerebral blood flow regulation.Indian journal of pharmacology · 2011Article
- α-Adrenergic vasoconstrictor responsiveness is preserved in the heated human leg.The Journal of physiology · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
Carotid baroreflex (CBR) function was examined in five men and three women (25 +/- 1 years) using the variable-pressure neck collar technique at rest and during dynamic, one-legged knee extension exercise at 7 W and 25 W. The CBR exhibited control of leg vascular conductance (LVC) at rest and during exercise in both an exercising leg (EL) and a non-exercising leg (NEL) across a wide range of pressures from +40 Torr neck pressure (NP) to -80 Torr neck suction (NS). Specifically, increases in LVC (% change) in response to NS were no different across -20 to -80 Torr in either EL or NEL compared to rest, P > 0.05. However, CBR-mediated decreases in percentage LVC in response to NP were attenuated in EL at both 7 W (16 +/- 1%) and 25 W (12 +/- 1%) compared to rest (40 +/- 3%; P < 0.05) as well as compared to responses in the NEL (36 +/- 6% at 7 W and 36 +/- 7% at 25 W; P < 0.05). This decrease in vascular responsiveness in EL was associated with a reduction in the gain of the percentage muscle sympathetic nerve activity (%MSNA)-%LVC relationship compared to rest (P < 0.05). Collectively, these data indicate that, despite a clear attenuation of the vascular response to MSNA in the exercising leg, CBR-mediated changes in mean arterial pressure were no different between rest and exercise.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.