Evidence map›Paper›PMID 15387349›Full record

ArticleDigestive diseases and sciences2004

Structural and neuronal changes in rat ileum after ischemia with reperfusion.

Lille-Mor Lindeström, Eva Ekblad

Abstract read
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In one paragraph

Article in Digestive diseases and sciences, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Nitrergic Enteric Neurons in Health and Disease-Focus on Animal Models.International journal of molecular sciences · 2019
    Review
  9. Establishment of an acute extraocular muscle injury model in cats.International journal of ophthalmology · 2018
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. The role of mast cells in ischemia and reperfusion injury.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2014
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Lille-Mor LindeströmDepartment of Physiological Sciences, Section of Neuroendocrine Cell Biology, Lund University, 22184 Lund, Sweden.
Eva Ekblad

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intestinal ischemia/reperfusion (I/R) is of profound importance in many clinical situations. The present study investigates short- and long-term changes, in particular in enteric neurons, but also with respect to the presence of eosinophilic leukocytes, goblet cells, and mast cells in the intestinal wall using an experimental model for intestinal I/R. Structural changes were also examined. Specimens from untreated, sham-operated, and ischemia (60 min)/reperfusion (1 hr-10 weeks) rat ileum were studied using histochemistry and morphometry. After I/R a marked acidophilia was noted in both submucous and myenteric neurons. This preceded a loss of myenteric, but not submucous, neurons. A low number of acidophilic neurons was noted also in sham-operated segments. Eosinophils and mast cells gradually increased after I/R and were notably found in smooth muscle and myenteric ganglia. Structural changes included mucosal shedding followed by restitution with an epithelium transiently containing a high number of goblet cells and a marked thickening of the muscular layers.

Indexed as

AnimalsCell CountEosinophilsFemaleHistocytochemistryHypertrophyIleumIntestinal MucosaMast CellsMyenteric PlexusNecrosisNeuronsRatsRats, Sprague-DawleyReperfusion Injury

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.