ArticleDigestive diseases and sciences2004
Double-peaked high-pressure zone at the esophagogastric junction in controls and in patients with a hiatal hernia: a study using high-resolution manometry.
Article in Digestive diseases and sciences, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 46 citations in OpenAlex.
- Assessment of esophagogastric junction morphology by dynamic real-time MRI: comparison of imaging features to high-resolution manometry.Japanese journal of radiology · 2022Article
- Endoscopic diagnosis of hiatus hernia under deep inspiration is not consistent with esophageal manometric diagnosis.Journal of gastroenterology · 2018Article
- Esophagogastric Junction Morphology and Distal Esophageal Acid Exposure.Digestive diseases and sciences · 2016Article
- Esophageal testing: What we have so far.World journal of gastrointestinal pathophysiology · 2016Review
- Long-term effects of anti-reflux surgery on the physiology of the esophagogastric junction.Surgical endoscopy · 2015Article
- Recorded lower esophageal pressures as a function of electronic sleeve placement and location of gastric pressure measurement in patients with hiatal hernia.Journal of neurogastroenterology and motility · 2013Article
- Clinical applications of esophageal impedance monitoring and high-resolution manometry.Current gastroenterology reports · 2012Review
- High resolution manometry and multichannel intraluminal impedance oesophageal manometry in clinical practice.Frontline gastroenterology · 2010Review
- The size of the esophageal hiatus in gastroesophageal reflux pathophysiology: outcome of intraoperative measurements.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2010Article
- High-resolution esophageal manometry: a time motion study.Canadian journal of gastroenterology = Journal canadien de gastroenterologie · 2008Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The lower esophageal high-pressure zone (HPZ) consists of the intrinsic lower esophageal sphincter (LES) and the diaphragmatic sphincter. In patients with a hiatal hernia these constituents are separated. We performed high-resolution manometry of the esophagogastric HPZ in six controls, six patients with a small hernia, and six patients with a large hernia. Prevalence of a double-peak pressure profile of the HPZ was noted. Pressures and distances between the peaks were assessed. Prevalence of the double-peak profile was similar between patients with a small hernia and controls, but patients with a large hernia showed a higher prevalence with inspiration (P < 0.05) than the others. The distance between the two peaks was larger in patients with a large hernia (P < 0.05). In conclusion, high-resolution manometry makes it possible to distinguish the diaphragmatic pressure component from the LES. Two pressure peaks can be found both in hernia patients and in healthy volunteers.
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