ArticleJournal of molecular evolution2004
Evolution of metazoan cell junction proteins: the scaffold protein MAGI and the transmembrane receptor tetraspanin in the demosponge Suberites domuncula.
Article in Journal of molecular evolution, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Regeneration in calcareous sponge relies on 'purse-string' mechanism and the rearrangements of actin cytoskeleton.Cell and tissue research · 2023Article
- Membrane Compartmentalization and Scaffold Proteins in Leukocyte Migration.Frontiers in cell and developmental biology · 2020Review
- Tetraspanin Scaffold Proteins Function as Key Regulators of Hematopoietic Stem Cells.Frontiers in cell and developmental biology · 2020Review
- Molecular characterization of tsetse's proboscis and its response to Trypanosoma congolense infection.PLoS neglected tropical diseases · 2017Article
- Occluding junctions of invertebrate epithelia.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2016Review
- Development of long-term primary cell aggregates from Mediterranean octocorals.In vitro cellular & developmental biology. Animal · 2015Article
- Evolution and Structural Analyses of Glossina morsitans (Diptera; Glossinidae) Tetraspanins.Insects · 2014Article
- Molecular cloning, sequence characterization and expression analysis of a CD63 homologue from the coleopteran beetle, Tenebrio molitor.International journal of molecular sciences · 2013Article
- Cellular and molecular processes leading to embryo formation in sponges: evidences for high conservation of processes throughout animal evolution.Development genes and evolution · 2013Review
- Freshwater sponges have functional, sealing epithelia with high transepithelial resistance and negative transepithelial potential.PloS one · 2010Article
- The evolution of vertebrate tetraspanins: gene loss, retention, and massive positive selection after whole genome duplications.BMC evolutionary biology · 2010Article
- Evolution of the MAGUK protein gene family in premetazoan lineages.BMC evolutionary biology · 2010Article
- Molecular evolution of the MAGUK family in metazoan genomes.BMC evolutionary biology · 2007Article
- Molecular control of serial module formation along the apical-basal axis in the sponge Lubomirskia baicalensis: silicateins, mannose-binding lectin and mago nashi.Development genes and evolution · 2006Article
- Allograft rejection in the mixed cell reaction system of the demosponge Suberites domuncula is controlled by differential expression of apoptotic genes.Immunogenetics · 2004Article
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7 authors.
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Abstract
Until recently the positioning of the sponges (phylum Porifera) within the metazoan systematics was hampered by the lack of molecular evidence for the existence of junctional structures in the surface cell layers. In this study two genes related to the tight junctions are characterized from the demosponge Suberites domuncula: tetraspanin (SDTM4SF), a cell surface receptor, and MAGI (SDMAGI), a MAGUK (membrane-associated guanylate kinase homologue) protein. Especially the MAGI protein is known in other metazoan animal phyla to exist exclusively in tight junctions. The characteristic domains of MAGI proteins (six PDZ domains, two WW domains, and a truncated guanylate kinase motif) are conserved in the sponge protein. The functional analysis of SDMAGI done by in situ hybridization shows its expression in the surface epithelial layers (exopinacoderm and endopinacoderm). Northern blot studies reveal that expression of SDMAGI and SDTM4SF increases after formation of the pinacoderm layer in the animals as well as in primmorphs. These results support earlier notions that sponges contain junctional structures. We conclude that sponges contain epithelia whose cells are organized by cell junctions.
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