ReviewThe Korean journal of parasitology2004
Pathogenic free-living amoebae in Korea.
Review in The Korean journal of parasitology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 34 citations in OpenAlex.
- Understanding the pathogenicity of Naegleria fowleri in association with N. fowleri antigen-1 (Nfa1).Parasites, hosts and diseases · 2024Review
- Molecular detection and genotype identification ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2022Article
- Acanthamoeba Infection in a Drowning Child.Ethiopian journal of health sciences · 2016Article
- Occurrence and molecular characterization of free-living amoeba species (Acanthamoeba, Hartmannella, and Saccamoeba limax) in various surface water resources of Iran.Parasitology research · 2015Article
- Genotyping of acanthamoeba isolated from surface and stagnant waters of qazvin, central iran.Iranian Red Crescent medical journal · 2013Article
- Microbial contamination of contact lens storage cases and domestic tap water of contact lens wearers.Wiener klinische Wochenschrift · 2012Article
- Naegleria fowleri lysate induces strong cytopathic effects and pro-inflammatory cytokine release in rat microglial cells.The Korean journal of parasitology · 2011Article
- The Nf-actin gene is an important factor for food-cup formation and cytotoxicity of pathogenic Naegleria fowleri.Parasitology research · 2010Article
- Contact-independent cell death of human microglial cells due to pathogenic Naegleria fowleri trophozoites.The Korean journal of parasitology · 2008Article
- Heat shock protein 70 of Naegleria fowleri is important factor for proliferation and in vitro cytotoxicity.Parasitology research · 2008Article
- Molecular cloning and characterization of a cytosolic heat shock protein 70 from Naegleria fowleri.Parasitology research · 2007Article
- Expression of the nfa1 gene cloned from pathogenic Naegleria fowleri in nonpathogenic N. gruberi enhances cytotoxicity against CHO target cells in vitro.Infection and immunity · 2005Article
- Role of the Nfa1 protein in pathogenic Naegleria fowleri cocultured with CHO target cells.Clinical and diagnostic laboratory immunology · 2005Article
- Coexistence ofWater, air, and soil pollutionArticle
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acanthamoeba and Naegleria are widely distributed in fresh water, soil and dust throughout the world, and cause meningoencephalitis or keratoconjunctivitis in humans and other mammals. Korean isolates, namely, Naegleria sp. YM-1 and Acanthamoeba sp. YM-2, YM-3, YM-4, YM-5, YM-6 and YM-7, were collected from sewage, water puddles, a storage reservoir, the gills of a fresh water fish, and by corneal washing. These isolates were categorized into three groups based on the mortalities of infected mice namely, highly virulent (YM-4), moderately virulent (YM-2, YM-5 and YM-7) and nonpathogenic (YM-3). In addition, a new species of Acanthamoeba was isolated from a freshwater fish in Korea and tentatively named Korean isolate YM-4. The morphologic characters of its cysts were similar to those of A. culbertsoni and A. royreba, which were previously designated as Acanthamoeba group III. Based on experimentally infected mouse mortality, Acanthamoeba YM-4 was highly virulent. The isoenzymes profile of Acanthamoeba YM-4 was similar to that of A. royreba. Moreover, an anti-Acanthamoeba YM-4 monoclonal antibody reacted only with Acanthamoeba YM-4, and not with A. culbertsoni. Random amplified polymorphic DNA marker analysis and RFLP analysis of mitochondrial DNA and of a 18S small subunit ribosomal RNA, placed Acanthamoeba YM-4 in a separate cluster based on phylogenic distances. Thus Acanthamoeba YM-4 was identified as a new species, and assigned Acanthamoeba sohi. Up to the year 2002 in Korea, two clinical cases were found to be infected with Acanthamoeba spp. These patients died of meningoencephalitis. In addition, one case of Acanthamoeba pneumonia with an immunodeficient status was reported and Acanthamoeba was detected in several cases of chronic relapsing corneal ulcer, chronic conjunctivitis, and keratitis.
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