Evidence map›Paper›PMID 15378797›Full record

ArticleWorld journal of gastroenterology2004

Clinical significance of preoperative regional intra-arterial infusion chemotherapy for advanced gastric cancer.

Cheng-Wu Zhang, Shou-Chun Zou, Dun Shi, Da-Jian Zhao

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in World journal of gastroenterology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04799548 (A Phase II Study of Neoadjuvant Transcatheter Arterial Chemoembolization(TACE)Plus PD-1 Antibody), which is not on this map. Cited by 14 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 5 pooled it
0.3field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04799548 phase2unknown statusnot on this mapstarted 2021, after this paper: background citation

A Phase II Study of Neoadjuvant Transcatheter Arterial Chemoembolization(TACE)Plus PD-1 Antibody (Tislelizumab) in the Locally Advanced Stomach Adenocarcinoma

TypeinterventionalSponsorShanghai Zhongshan HospitalRan2021 to 2026Enrolled71ConditionsAdvanced Gastric CancerArmsTranscatheter Arterial Chemoembolization, Tislelizumab
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 5 syntheses or guidelines pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Trial
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Cheng-Wu ZhangDepartment of General Surgery, Zhejiang Provincial People's Hospital, Hangzhou 310014, Zhejiang Province, China. zcw1989@sina.com
Shou-Chun Zou
Dun Shi
Da-Jian Zhao
Zhejiang Provincial People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimPreoperative intra-arterial infusion chemotherapy could increase the radical resection rate of advanced gastric cancer, but its effect on the long-term survival has not been assessed. This study was designed to evaluate the clinical significance of preoperative intra-arterial infusion chemotherapy for advanced gastric cancer.

methodsClinicopathological data of 91 patients who underwent curative resection for advanced gastric cancer were collected. Among them, 37 patients undertaken preoperative intra-arterial infusion chemotherapy were used as the interventional chemotherapy group, and the remaining 54 patients as the control group. Eleven factors including clinicopathological variables, treatment procedures and molecular biological makers that might contribute to the long-term survival rate were analyzed using Cox multivariate regression analysis.

resultsThe 5-year survival rate was 52.5% and 39.8%, respectively, for the interventional group and the control group (P<0.05). Cox multivariate regression analysis revealed that the TNM stage (P<0.001), preoperative intra-arterial infusion chemotherapy (P = 0.029) and growth pattern (P = 0.042) were the independent factors for the long-term survival of patients with advanced gastric cancer.

conclusionPreoperative intra-arterial infusion chemotherapy plays an important role in improving the prognosis of advanced gastric cancer.

Indexed as

AdenocarcinomaAdultAgedCombined Modality TherapyFemaleHumansInfusions, Intra-ArterialMaleMiddle AgedMultivariate AnalysisPreoperative CarePrognosisProportional Hazards ModelsRetrospective StudiesStomach Neoplasms

Identifiers

PMID15378797
PMCPMC4576275
OpenAlexW2182764391

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.