Evidence map›Paper›PMID 15378391›Full record

ReviewInvertebrate neuroscience : IN2004

Proctolin in the post-genomic era: new insights and challenges.

R Elwyn Isaac, Christine A Taylor, Yasutaka Hamasaka, Dick R Nässel, Alan D Shirras

Abstract readReview
PubMed Publisher
In one paragraph

Review in Invertebrate neuroscience : IN, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Short neuropeptide F in integrated insect physiology.Journal of Zhejiang University. Science. B · 2024
    Review
  2. Review
  3. Review
  4. Peptidomics of Neuropeptidergic Tissues of the Tsetse Fly Glossina morsitans morsitans.Journal of the American Society for Mass Spectrometry · 2015
    Article
  5. Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

R Elwyn IsaacMolecular and Cellular Biology Research Group, Faculty of Biological Sciences, L.C. Miall Building, University of Leeds, LS2 9JT, Leeds, UK. r.e.isaac@leeds.ac.uk
Christine A Taylor
Yasutaka Hamasaka
Dick R Nässel
Alan D Shirras

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Complete understanding of how neuropeptides operate as neuromodulators and neurohormones requires integration of knowledge obtained at different levels of biology, including molecular, biochemical, physiological and whole organism studies. Major advances have recently been made in the understanding of the molecular basis of neuropeptide action in invertebrates by analysis of data generated from sequencing the genomes of several insect species, especially that of Drosophila melanogaster. This approach has quickly led to the identification of genes encoding: (1) novel neuropeptide sequences, (2) neuropeptide receptors and (3) peptidases that might be responsible for the processing and inactivation of neuropeptides. In this article, we review our current knowledge of the biosynthesis, receptor interaction and metabolic inactivation of the arthropod neuropeptide, proctolin, and how the analysis and exploitation of genome sequencing projects has provided new insights.

Indexed as

GenomeAmino Acid SequenceAnimalsComputational BiologyDatabases, ProteinInsectaInsect ProteinsNeuropeptidesOligopeptidesReceptors, NeuropeptideInsect ProteinsNeuropeptidesOligopeptidesproctolinReceptors, Neuropeptide

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.