ArticleHistochemistry and cell biology2004
Intraganglionic laminar endings and their relationships with neuronal and glial structures of myenteric ganglia in the esophagus of rat and mouse.
Article in Histochemistry and cell biology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Topographical organization and morphology of substance P (SP)-immunoreactive axons in the whole stomach of mice.The Journal of comparative neurology · 2023Article
- Effect of old age on the subpopulations of enteric glial cells in human descending colon.Glia · 2023Article
- The complex involvement of the digestive tract in human defense behavior - structural and functional arguments.Journal of medicine and life · 2022Review
- Enteric glia in homeostasis and disease: From fundamental biology to human pathology.iScience · 2021Review
- Murine Esophagus Expresses Glial-Derived Central Nervous System Antigens.International journal of molecular sciences · 2021Article
- Vagus Nerves Provide a Robust Afferent Innervation of the Mucosa Throughout the Body of the Esophagus in the Mouse.Dysphagia · 2020Article
- Endogenous Glutamate Excites Myenteric Calbindin Neurons by Activating Group I Metabotropic Glutamate Receptors in the Mouse Colon.Frontiers in neuroscience · 2019Article
- Homer1 (VesL-1) in the rat esophagus: focus on myenteric plexus and neuromuscular junction.Histochemistry and cell biology · 2017Article
- Involvement of catecholaminergic neurons in motor innervation of striated muscle in the mouse esophagus.Histochemistry and cell biology · 2016Article
- Morphology of P2X3-immunoreactive nerve endings in the rat laryngeal mucosa.Histochemistry and cell biology · 2016Article
- Distribution of transient receptor potential cation channel subfamily V member 1-expressing nerve fibers in mouse esophagus.Histochemistry and cell biology · 2014Article
- Localization of receptors for calcitonin-gene-related peptide to intraganglionic laminar endings of the mouse esophagus: peripheral interaction between vagal and spinal afferents?Histochemistry and cell biology · 2014Article
- Morphology and chemical characteristics of subepithelial laminar nerve endings in the rat epiglottic mucosa.Histochemistry and cell biology · 2012Article
- Expression of vesicular glutamate transporters type 1 and 2 in sensory and autonomic neurons innervating the mouse colorectum.The Journal of comparative neurology · 2011Article
- Vagal intramuscular array afferents form complexes with interstitial cells of Cajal in gastrointestinal smooth muscle: analogues of muscle spindle organs?Neuroscience · 2011Article
- Metabotropic glutamate receptors as novel therapeutic targets on visceral sensory pathways.Frontiers in neuroscience · 2011Article
- Biomechanical and histomorphometric colon remodelling in STZ-induced diabetic rats.Digestive diseases and sciences · 2009Article
- Nitric oxide as an endogenous peripheral modulator of visceral sensory neuronal function.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2009Article
- Distribution of P2X(3) receptor immunoreactivity in myenteric ganglia of the mouse esophagus.Histochemistry and cell biology · 2009Article
- Vagal and hormonal gut-brain communication: from satiation to satisfaction.Neurogastroenterology and motility · 2008Review
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intraganglionic laminar endings (IGLEs) represent the only vagal mechanosensory terminals in the tunica muscularis of the esophagus and may be involved in local reflex control. We recently detected extensive though not complete colocalization of the vesicular glutamate transporter 2 (VGLUT2) with markers for IGLEs. To elucidate this colocalization mismatch, this study aimed at identifying markers for nitrergic, cholinergic, peptidergic, and adrenergic neurons and glial cells, which may colocalize with VGLUT2 outside of IGLEs. Confocal imaging revealed, besides substantial colocalization of VGLUT2 and substance P (SP), no other significant colocalizations of VGLUT2 and immunoreactivity for any of these markers within the same varicosities. However, we found close contacts of VGLUT2-positive structures to vesicular acetylcholine transporter, choline acetyltransferase, neuronal nitric oxide synthase, galanin, neuropeptide Y, and vasoactive intestinal peptide immunoreactive cell bodies and varicosities, as well as to glial cells. Neuronal perikarya were never positive for VGLUT2. Thus, VGLUT2 was almost exclusively found in IGLEs and may serve as a specific marker for them. In addition, many IGLEs also contained SP. The close contacts established by IGLEs to myenteric cell bodies, dendrites, and varicose fibers suggest that IGLEs modulate various types of enteric neurons and vice versa.
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