Evidence map›Paper›PMID 15378222›Full record

ArticleEuropean journal of clinical pharmacology2004

Bridging the gap between therapeutic research results and physician prescribing decisions: knowledge transfer, a prerequisite to knowledge translation.

Jean-Pierre Boissel, Emmanuel Amsallem, Michel Cucherat, Patrice Nony, Margaret C Haugh

Abstract read
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In one paragraph

Article in European journal of clinical pharmacology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Facilitating the implementation of empirically valid interventions in psychosocial oncology and supportive care.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2011
    Pooled it
  2. Systems Biology Approaches for Therapeutics Development Against COVID-19.Frontiers in cellular and infection microbiology · 2020
    Review
  3. Article
  4. Bridging Systems Medicine and Patient Needs.CPT: pharmacometrics & systems pharmacology · 2015
    Review
  5. Article
  6. Clinical pharmacology in everyday clinical care.European journal of clinical pharmacology · 2013
    Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jean-Pierre BoisselFaculté RTH Laennec, Service de Pharmacologie Clinique (EA3736), rue Guillaume Paradin, 69376, Lyon Cedex 08, France. jpb@upcl.univ-lyon1.fr
Emmanuel Amsallem
Michel Cucherat
Patrice Nony
Margaret C Haugh

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA wide gap continues to exist between available therapeutic research results and physician's prescribing. Numerous explanations account for this gap, but one central reason is the difficulty in transferring comprehensive research information to practicing clinicians. This problem arises from information overload and the growing complexity of research findings. We propose a multistep process that can be used to develop systems to bridge this information/prescription gap. The steps include: comprehensively collecting and summarizing clinical trial reports, scoring and ranking these according to their level of evidence, exploring and synthesizing the data using meta-analyses, summarizing these results, representing them in an easily understandable form, and transmitting the overview findings to prescribers at the time they need them. DISCUSSION: This ambitious endeavor is needed to ensure that prescribers have access to pertinent research results for use in their prescription decisions. We demonstrate in this article that there are no theoretical or technical obstacles to make the proposed system workable.

Indexed as

Clinical CompetenceDrug Information ServicesPractice Patterns, Physicians'ResearchDecision Support TechniquesDrug TherapyEvidence-Based MedicineHumansInformation DisseminationPractice Guidelines as TopicTime Factors

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.