Evidence map›Paper›PMID 15377787›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2004

High-throughput microarray detection of olfactory receptor gene expression in the mouse.

Xinmin Zhang, Matthew Rogers, Huikai Tian, Xiaohong Zhang, Dong-Jing Zou, Jian Liu, Minghong Ma, Gordon M Shepherd, Stuart J Firestein

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers.

0numbers the graph read from it
0cells of the map it votes in
90citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

90 citing papers in PubMed, 168 citations in OpenAlex.

  1. Review
  2. Order code in the olfactory system.bioRxiv : the preprint server for biology · 2025
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  15. Immunocytochemical Localization of Olfactory-signaling Molecules in Human and Rat Spermatozoa.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2020
    Article
  16. Article
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  20. Review

30 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Xinmin ZhangDepartment of Biological Sciences, Columbia University, New York, NY 10027, USA.
Matthew Rogers
Huikai Tian
Xiaohong Zhang
Dong-Jing Zou
Jian Liu
Minghong Ma
Gordon M Shepherd
Stuart J Firestein
Yale University · USColumbia University · US

Funding

Functional Characterization of the Septal OrganR03DC005127 · NIDCD · UNIVERSITY OF PENNSYLVANIA · PI MA, MINGHONG · 2001 to 2003
$242k
NIDCD NIH HHS R03 DC005127
6 · The paper itself

Abstract

The large number of olfactory receptor genes necessitates high throughput methods to analyze their expression patterns. We have therefore designed a high-density oligonucleotide array containing all known mouse olfactory receptor (OR) and V1R vomeronasal receptor genes. This custom array detected a large number of receptor genes, demonstrating specific expression in the olfactory sensory epithelium for approximately 800 OR genes previously designated as ORs based solely on genomic sequences. The array also enabled us to monitor the spatial and temporal distribution of gene expression for the entire OR family. Interestingly, OR genes showing spatially segregated expression patterns were also segregated on the chromosomes. This correlation between genomic location and spatial expression provides unique insights about the regulation of this large family of genes.

Indexed as

Age FactorsAnimalsChromosomesCluster AnalysisGene Expression ProfilingGenomeLungMaleMiceMice, Inbred StrainsOlfactory MucosaOligonucleotide Array Sequence AnalysisReceptors, OdorantTestisVomeronasal OrganReceptors, Odorant

Identifiers

PMID15377787
PMCPMC521132
OpenAlexW1983646382

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.