ArticleThe Plant cell2004
A classical arabinogalactan protein is essential for the initiation of female gametogenesis in Arabidopsis.
Article in The Plant cell, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers.
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Who cites it
84 citing papers in PubMed, 189 citations in OpenAlex.
- Basis of apomixis in flowering plants - state of the art and research perspectives.Plant reproduction · 2026Review
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- The Arabidopsis KASH protein SINE3 is involved in male and female gametogenesis.Plant reproduction · 2024Article
- JAGGER localization and function are dependent on GPI anchor addition.Plant reproduction · 2024Article
- Cluster effect through the oligomerisation of bioactive disaccharide AMOR on pollen tube capacitation inRSC chemical biology · 2024Article
- Article
- Knockout of eightCell surface (Amsterdam, Netherlands) · 2023Article
- AGPs as molecular determinants of reproductive development.Annals of botany · 2023Article
- Spatiotemporal formation of the large vacuole regulated by the BIN2-VLG module is required for female gametophyte development in Arabidopsis.The Plant cell · 2023Article
- Genetic and Phenotypic Analysis of Ovule Development in Arabidopsis.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Arabinogalactan Proteins: Focus on the Role in Cellulose Synthesis and Deposition during Plant Cell Wall Biogenesis.International journal of molecular sciences · 2022Review
- New insights on the expression patterns of specific Arabinogalactan proteins in reproductive tissues ofFrontiers in plant science · 2022Article
- Links between Regulatory Systems of ROS and Carbohydrates in Reproductive Development.Plants (Basel, Switzerland) · 2021Review
- Article
- Arabinogalactan glycoprotein dynamics during the progamic phase in the tomato pistil.Plant reproduction · 2021Article
- The Role of Arabinogalactan Type II Degradation in Plant-Microbe Interactions.Frontiers in microbiology · 2021Review
- Arabinogalactan Proteins in Plant Roots - An Update on Possible Functions.Frontiers in plant science · 2021Review
- Bridging the GAPs in plant reproduction: a comparison of plant and animal GPI-anchored proteins.Plant reproduction · 2020Review
- AtPIG-S, a predicted Glycosylphosphatidylinositol Transamidase subunit, is critical for pollen tube growth in Arabidopsis.BMC plant biology · 2020Article
- Identification and characterization of a female gametophyte defect inPlant signaling & behavior · 2020Article
24 more citing papers are in PubMed but not listed here.
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Classical arabinogalactan proteins (AGPs) are an abundant class of cell surface proteoglycans widely distributed in flowering plants. We have used a combination of enhancer detection tagging and RNA interference (RNAi)-induced posttrancriptional silencing to demonstrate that AGP18, a gene encoding a classical arabinogalactan protein, is essential for female gametogenesis in Arabidopsis thaliana. AGP18 is expressed in cells that spatially and temporally define the sporophytic to gametophytic transition and during early stages of seed development. More than 75% of the T1 transformants resulted in T2 lines showing reduced seed set during at least three consecutive generations but no additional developmental defects. AGP18-silenced T2 lines showed reduced AGP18 transcript levels in female reproductive organs, the presence of 21-bp RNA fragments specific to the AGP18 gene, and the absence of in situ AGP18 mRNA localization in developing ovules. Reciprocal crosses to wild-type plants indicate that the defect is female specific. The genetic and molecular analysis of AGP18-silenced plants containing a single T-DNA RNAi insertion suggests that posttranscriptional silencing of AGP18 is acting both at the sporophytic and gametophytic levels. A cytological analysis of all defective AGP18-RNAi lines, combined with the analysis of molecular markers acting at key stages of female gametogenesis, showed that the functional megaspore fails to enlarge and mitotically divide, indicating that AGP18 is essential to initiate female gametogenesis in Arabidopsis. Our results assign a specific function in plant development to a gene encoding a classical AGP.
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