ArticleBiophysical journal2004
High resolution magnetic images of planar wave fronts reveal bidomain properties of cardiac tissue.
Article in Biophysical journal, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Magnetic field based investigation of Brugada syndrome.European biophysics journal : EBJ · 2026Article
- Non-invasive mapping of ventricular action potential waveforms reconstructed from clinical unshielded magnetocardiography. Potential diagnostic application and current limitations.American heart journal plus : cardiology research and practice · 2025Article
- An advanced vision of magnetocardiography as an unrivalled method for a more comprehensive non-invasive clinical electrophysiological assessment.American heart journal plus : cardiology research and practice · 2025Article
- The magnetocardiogram.Biophysics reviews · 2024Review
- Biomagnetism: The First Sixty Years.Sensors (Basel, Switzerland) · 2023Review
- Bidomain modeling of electrical and mechanical properties of cardiac tissue.Biophysics reviews · 2021Review
- Measurements of transmembrane potential and magnetic field at the apex of the heart.Biophysical journal · 2010Article
- Partial independence of bioelectric and biomagnetic fields and its implications for encephalography and cardiography.Physical review. E, Statistical, nonlinear, and soft matter physics · 2009Article
- Interpreting biomagnetic fields of planar wave fronts in cardiac muscle.Biophysical journal · 2005Article
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5 authors.
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Abstract
We magnetically imaged the magnetic action field and optically imaged the transmembrane potentials generated by planar wavefronts on the surface of the left ventricular wall of Langendorff-perfused isolated rabbit hearts. The magnetic action field images were used to produce a time series of two-dimensional action current maps. Overlaying epifluorescent images allowed us to identify a net current along the wavefront and perpendicular to gradients in the transmembrane potential. This is in contrast to a traditional uniform double-layer model where the net current flows along the gradient in the transmembrane potential. Our findings are supported by numerical simulations that treat cardiac tissue as a bidomain with unequal anisotropies in the intra- and extracellular spaces. Our measurements reveal the anisotropic bidomain nature of cardiac tissue during plane wave propagation. These bidomain effects play an important role in the generation of the whole-heart magnetocardiogram and cannot be ignored.
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