ArticleEMBO reports2004
The DNA repair helicase UvrD is essential for replication fork reversal in replication mutants.
Article in EMBO reports, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed.
- The separation pin distinguishes the pro- and anti-recombinogenic functions of Saccharomyces cerevisiae Srs2.Nature communications · 2023Article
- PcrA Dissociates RecA Filaments and the SsbA and RecO Mediators Counterbalance Such Activity.Frontiers in molecular biosciences · 2022Article
- Kinetic and structural mechanism for DNA unwinding by a non-hexameric helicase.Nature communications · 2021Article
- Srs2 and Pif1 as Model Systems for Understanding Sf1a and Sf1b Helicase Structure and Function.Genes · 2021Review
- Single Strand Annealing Plays a Major Role in RecA-Independent Recombination between Repeated Sequences in the Radioresistant Deinococcus radiodurans Bacterium.PLoS genetics · 2015Article
- Genomics Analysis of Replicative Helicase DnaB Sequences in Proteobacteria.Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH · 2014Article
- Proteomic analysis of the effect of diclazuril on second-generation merozoites of Eimeria tenella.Parasitology research · 2014Article
- Homologous recombination as a replication fork escort: fork-protection and recovery.Biomolecules · 2012Article
- Single-stranded DNA translocation of E. coli UvrD monomer is tightly coupled to ATP hydrolysis.Journal of molecular biology · 2012Article
- Resolving Holliday junctions with Escherichia coli UvrD helicase.The Journal of biological chemistry · 2012Article
- Rotations of the 2B sub-domain of E. coli UvrD helicase/translocase coupled to nucleotide and DNA binding.Journal of molecular biology · 2011Article
- DNA tandem repeat instability in the Escherichia coli chromosome is stimulated by mismatch repair at an adjacent CAG·CTG trinucleotide repeat.Proceedings of the National Academy of Sciences of the United States of America · 2010Article
- 5'-Single-stranded/duplex DNA junctions are loading sites for E. coli UvrD translocase.The EMBO journal · 2010Article
- Srs2: the "Odd-Job Man" in DNA repair.DNA repair · 2010Review
- Characterization of the mycobacterial NER system reveals novel functions of the uvrD1 helicase.Journal of bacteriology · 2009Article
- Comparative genomics and molecular dynamics of DNA repeats in eukaryotes.Microbiology and molecular biology reviews : MMBR · 2008Review
- UvrD and UvrD252 counteract RecQ, RecJ, and RecFOR in a rep mutant of Escherichia coli.Journal of bacteriology · 2008Article
- Cleavage of stalled forks by fission yeast Mus81/Eme1 in absence of DNA replication checkpoint.Molecular biology of the cell · 2008Article
- Two closely related RecQ helicases have antagonistic roles in homologous recombination and DNA repair in Arabidopsis thaliana.Proceedings of the National Academy of Sciences of the United States of America · 2007Article
- Recent advances in the expression, evolution, and dynamics of prokaryotic genomes.Journal of bacteriology · 2007Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Replication forks arrested by inactivation of the main Escherichia coli DNA polymerase (polymerase III) are reversed by the annealing of newly synthesized leading- and lagging-strand ends. Reversed forks are reset by the action of RecBC on the DNA double-strand end, and in the absence of RecBC chromosomes are linearized by the Holliday junction resolvase RuvABC. We report here that the UvrD helicase is essential for RuvABC-dependent chromosome linearization in E. coli polymerase III mutants, whereas its partners in DNA repair (UvrA/B and MutL/S) are not. We conclude that UvrD participates in replication fork reversal in E. coli.
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