ArticleThe Journal of physiology2004
Chronometric readout from a memory trace: gamma-frequency field stimulation recruits timed recurrent activity in the rat CA3 network.
Article in The Journal of physiology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Network Desynchronization with Sine Waves: from Synchrony to Asynchrony by Periodic Stimulation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Modulating excitation/inhibition balance through transcranial electrical stimulation: physiological mechanisms in animal models.Frontiers in neuroscience · 2025Review
- Computing with electromagnetic fields rather than binary digits: a route towards artificial general intelligence and conscious AI.Frontiers in systems neuroscience · 2025Article
- Neurophysiological mechanisms of transcranial alternating current stimulation.Frontiers in neuroscience · 2023Review
- Biophysically grounded mean-field models of neural populations under electrical stimulation.PLoS computational biology · 2020Article
- Integrating information in the brain's EM field: the cemi field theory of consciousness.Neuroscience of consciousness · 2020Article
- An ephaptic transmission model of CA3 pyramidal cells: an investigation into electric field effects.Cognitive neurodynamics · 2014Article
- Effects of weak transcranial alternating current stimulation on brain activity-a review of known mechanisms from animal studies.Frontiers in human neuroscience · 2013Review
- NMDA antagonists recreate signal-to-noise ratio and timing perturbations present in schizophrenia.Neurobiology of disease · 2012Article
- Low-intensity electrical stimulation affects network dynamics by modulating population rate and spike timing.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2010Article
- Oscillatory phase coupling coordinates anatomically dispersed functional cell assemblies.Proceedings of the National Academy of Sciences of the United States of America · 2010Article
- Transcranial electric stimulation entrains cortical neuronal populations in rats.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2010Article
- Article
- Field effects in the CNS play functional roles.Frontiers in neural circuits · 2010Article
- Neurophysiological endophenotypes across bipolar and schizophrenia psychosis.Schizophrenia bulletin · 2008Review
- A recurrent network in the lateral amygdala: a mechanism for coincidence detection.Frontiers in neural circuits · 2008Article
- Sensitivity of coherent oscillations in rat hippocampus to AC electric fields.The Journal of physiology · 2007Article
- Spike timing amplifies the effect of electric fields on neurons: implications for endogenous field effects.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2007Article
- Controlling the local extracellular electric field can suppress the generation and propagation of seizures and spikes in the hippocampus.Brain stimulationArticle
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Synchronous population activity is prevalent in neurones of the central nervous system and experimentally captured as oscillatory electric fields, the frequency of which can represent the state of the neural circuit, e.g. theta (approximately 5 Hz) and gamma (approximately 40 Hz). Such field oscillations, however, are not merely a result of coherent neuronal activity. They may also play active roles in information processing in the brain. In this study, we observed that, in cultured hippocampal slices, CA3 pyramidal cells responded to single-pulse stimuli with monosynaptic and polysynaptic potentials and firing spikes which occurred after variable latencies. The variability of the spike latencies was greatly reduced in the presence of weak electric field oscillations, especially the oscillation in the gamma-band frequency range, that per se induced only small fluctuations in the subthreshold membrane potential, and this effect was inhibited by blockade of NMDA receptor activity. Furthermore, the latency of the firing spikes changed if the stimulus was applied at a different phase of the imposed gamma oscillations. These results may suggest that the background field oscillations serve as an extracellular time reference and assure accurate and stable decoding of a memory trace present in cortical feedback networks.
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